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Total of 467 results See all subject areas
genetics

Background. Previous research has supported gender-specific aetiological factors in oppositional defiant disorder (ODD) and conduct disorder (CD). The aims of this study were to identify gender-specific associations between the behavioural problems–ODD/CD-like...

["Genetics","Epidemiology","Psychiatry and Psychology"]
doi:10.7717/peerj.359

Purpose. To design and validate a prenatal chromosomal microarray testing strategy that moves away from size-based detection thresholds, towards a more clinically relevant analysis, providing higher resolution than G-banded chromosomes but avoiding the detection...

["Genetics","Medical Genetics","Ethical Issues"]
doi:10.7717/peerj.354

It has been widely accepted that aphids and their primary endosymbiotic bacteria Buchnera have strictly parallel diversification relationship. As the first reported case of insect-bacteria cospeciation, this parallel diversification hypothesis has been prevalent,...

["Entomology","Evolutionary Studies","Genetics","Microbiology","Zoology"]
doi:10.7287/peerj.preprints.346v1

Contagious parthenogenesis – a process involving rare functional males produced by a parthenogenetic lineage, which mate with coexisting sexual females resulting in fertile parthenogenetic offspring – is one of the most striking mechanisms responsible for the generation...

["Biodiversity","Evolutionary Studies","Genetics","Zoology"]
doi:10.7287/peerj.preprints.333v1

Obesity in human populations, currently a serious health concern, is considered to be the consequence of an energy imbalance in which more energy in calories is consumed than is expended. We used interval mapping techniques to investigate the genetic basis of a...

["Genetics"]
doi:10.7287/peerj.preprints.311v1

Bacteria were long assumed to be monoploid, maintaining one copy of a circular chromosome. In recent years it became obvious that the majority of species in several phylogenetic groups of prokaryotes are oligoploid or polyploid, e.g. in halophilic and methanogenic...

["Biochemistry","Genetics","Genomics","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.306v1

In Drosophila, iron is stored in the endomembrane system of cells inside a protein cavity formed by 24 ferritin subunits of two types (Fer1HCH and Fer2LCH) in a 1:1 stoichiometry. Ferritin accumulates in the midgut, nervous system, hemolymph and nephrocytes of...

["Cell Biology","Developmental Biology","Genetics"]
doi:10.7287/peerj.preprints.301v1

Brown-headed Cowbirds (Molothrus ater) are the most widespread avian brood parasite in North America, laying their eggs in the nests of approximately 250 host species that raise the cowbird nestlings as their own. It is currently unknown how these heterospecific...

["Evolutionary Studies","Genetics","Microbiology","Zoology"]
doi:10.7717/peerj.321

William Bateson’s background and training suggest sympathy with the black emancipation movement. Yet the movement’s success is attributed more to battles between political figures, than between scientists with contending views on the biology of racial differences....

["Evolutionary Studies","Genetics","Ethical Issues","Legal Issues","Science Policy"]
doi:10.7287/peerj.preprints.294v1

Severe fragmentation is a typical fate of native remnant habitats in cities, and urban wildlife with limited dispersal ability are predicted to lose genetic variation in isolated urban patches. However, little information exists on the characteristics of urban...

["Conservation Biology","Ecology","Evolutionary Studies","Genetics","Zoology"]
doi:10.7717/peerj.310

We examine heritability estimation of an ordinal trait for osteoarthritis, using a population of pig-tailed macaques from the Washington National Primate Research Center (WaNPRC). This estimation is non-trivial, as the data consist of ordinal measurements on 16...

["Genetics","Orthopedics","Statistics"]
doi:10.7287/peerj.preprints.284v1

Pendred syndrome (PDS) and DFNB4 comprise a phenotypic spectrum of sensorineural hearing loss disorders that typically result from biallelic mutations of the SLC26A4 gene. Although PDS and DFNB4 are recessively inherited, sequencing of the coding regions and splice...

["Genetics","Medical Genetics","Otorhinolaryngology","Pathology","Pediatrics"]
doi:10.7287/peerj.preprints.275v1

Background: The phylogeny of birds which are adapted to aquatic environments is controversial because of convergent evolution. Methods: To understand water bird evolution in more detail, we sequenced the majority of mitochondrial protein coding genes (6699 nucleotides...

["Biodiversity","Evolutionary Studies","Genetics","Genomics","Zoology"]
doi:10.7287/peerj.preprints.272v1

Many microbial, fungal, or oomcyete populations violate assumptions for population genetic analysis because these populations are clonal, admixed, partially clonal, and/or sexual. Furthermore, few tools exist that are specifically designed for analyzing data from...

["Bioinformatics","Genetics","Microbiology","Mycology","Computational Science"]
doi:10.7717/peerj.281

Severe fragmentation is a typical fate of native remnant habitats in cities, and urban wildlife with limited dispersal ability are predicted to lose genetic variation in isolated urban patches. However, little information exists on the characteristics of urban...

["Conservation Biology","Ecology","Evolutionary Studies","Genetics","Zoology"]
doi:10.7287/peerj.preprints.165v2

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