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Total of 208 results See all subject areas
biotechnology

With rising environmental concerns on potable water safety and eutrophication, increased media attention and tighter environmental regulations, managing animal waste in an environmentally responsible and economically feasible way can be a challenge. In this study,...

["Biotechnology","Environmental Sciences"]
doi:10.7717/peerj.336

The feasibility of disrupting a tumor’s vascular structure with various radiation types and radionuclides is investigated. Calculated absorbed dose profiles for photons and 4He ions suggest that low-energy beta-gamma and alpha emitting radionuclides can deposit...

["Biophysics","Biotechnology","Radiology and Medical Imaging"]
doi:10.7717/peerj.320

Aims: Adeno-associated virus type 2 (AAV2) is a naturally defective human parvovirus that is being developed as a gene therapy vector. In dividing cells, AAV2 DNA persists by integration into the host chromosomes. AAV2 is unique among mammalian viruses in its ability...

["Biotechnology","Molecular Biology","Virology"]
doi:10.7287/peerj.preprints.326v1

We show for the first time the effects of heavy-hydrogen water (2H2O) and heavy-oxygen water (H218O) on the gliding speed of microtubules on kinesin-1 coated surfaces. Increased fractions of isotopic waters used in the motility solution decreased the gliding speed...

["Biophysics","Biotechnology"]
doi:10.7717/peerj.284

With rising environmental concerns on potable watersafety and eutrophication, increased media attention and tighter environmental regulations, managing animal wastes in an environmentally responsible and economically feasible way can be a challenge. In this study,...

["Biotechnology","Environmental Sciences"]
doi:10.7287/peerj.preprints.271v1

Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) comprise a powerful class of tools that are redefining the boundaries of biological research. Although these technologies have begun to enable targeted genome modifications,...

["Biotechnology","Genetics","Genomics"]
doi:10.7287/peerj.preprints.229v1

Antimycins are an extended family of depsipeptides that are made by filamentous actinomycete bacteria and were first isolated more than 60 years ago. Recently, antimycins have attracted renewed interest because of their activities against the anti-apoptotic machineries...

["Biochemistry","Biotechnology","Microbiology","Molecular Biology"]
doi:10.7287/peerj.preprints.203v1

A novel degradation pathway of 2-chloro-4-aminophenol (2C4AP) was studied in an Arthrobacter sp. SPG that utilized 2C4AP as a sole carbon and energy source. The 2C4AP degradation was initiated by a 2C4AP-deaminase that catalyzed the conversion of 2C4AP into chlorohydroquinone...

["Agricultural Science","Biochemistry","Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.194v1

Stem cells have the remarkable potential to develop into many different specialized cells in the body. Serving as a sort of repair system for the body, they can theoretically divide without limit to repletion other cells as long as the person or animal is still...

["Biotechnology"]
doi:10.7287/peerj.preprints.148v1

Sufficient quantities of cells of consistent characteristics are needed for studying processes - at the population level and beyond - in many areas of applied microbiology research. Nevertheless, given the relatively low biomass yield of many commercial culture...

["Biochemistry","Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.115v2

The characteristics of the culture vessel determine, to a large extent, the type of growth medium suitable for use. For example, most growth media for high cell density cultivation are designed for expensive bioreactors operating either in continuous or fed-batch...

["Biochemistry","Biotechnology","Microbiology"]
doi:10.7287/peerj.preprints.117v1

Zeta potential - defined as the electrical charge at the shear plane - is widely used as a proxy for cell surface charge. Consequent of its definition, nonspecific adsorption of ions on the cell surface may alter the value - and polarity - of the measured zeta...

["Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.110v1

The East Indian Sandalwood tree, Santalum album L. has been widely used in folk medicine for treatment of common colds, bronchitis, skin disorders, heart ailments, general weakness, fever, infection of the urinary tract, inflammation of the mouth and pharynx, liver...

["Biotechnology","Plant Science","Evidence Based Medicine","Global Health","Pharmacology"]
doi:10.7287/peerj.preprints.96v1

Bacterial surface charge (SC) mediates important cell-environment and microbe-host interactions, and its accurate and precise measurement by microelectrophoresis requires removing metabolites adhered to the cell surface - where repeated centrifugation and washing...

["Biotechnology","Environmental Sciences","Microbiology"]
doi:10.7287/peerj.preprints.91v1

Natural photosynthesis allows biological systems to remarkably combine carbon dioxide and water molecules under sunlight to produce energy in the form of stored sugars. The stored sugar is then used by plants and animals to exert vital biological functions. If...

["Bioengineering","Biotechnology","Plant Science","Synthetic Biology"]
doi:10.7287/peerj.preprints.66v1

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