78 downloads
100 views

Bioinformatics is an interdisciplinary field that develops software methods and tools to understand biological data. Actually, in branches such as genomics, there are a large number of software tools that serve to support different processes such as genetic data...

["Bioinformatics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.27352v2
1,413 downloads
3,391 views

This article proposes quantitative answers to meta-scientific questions including "how much knowledge is attained by a research field?","how rapidly is a field making progress?", "what is the expected reproducibility of a result?", "how much knowledge is lost from...

["Computational Biology","Ethical Issues","Science Policy","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.1968v5

Nowadays, the analysis of RNA-seq and BS-Seq can be considered well established, whereas the analysis of broad peaks data as Sono-Seq/ATAC-Seq and histone modification (HM) ChIP-Seq is still challenging. To fill the gap in existing methods, we present DEScan2 a...

["Bioinformatics","Genomics"]
doi:10.7287/peerj.preprints.27357v1

Background Ebola Virus Disease (EVD) is a highly infectious disease that has produced over 25,000 cases in the past 50 years. While many past outbreaks resulted in relatively few cases, the 2014 outbreak in West Africa was the most deadly occurrence of EVD to date,...

["Epidemiology","Infectious Diseases","Statistics"]
doi:10.7717/peerj.5888
1 download
1 view

Articular cartilage is an avascular tissue with limited regenerative property. Therefore, a defect or trauma in articular cartilage due to disease or accident can lead to progressive tissue deterioration. Cartilage tissue engineering, by replacing defective cartilage...

["Bioengineering","Biotechnology","Cell Biology","Developmental Biology","Translational Medicine"]
doi:10.7717/peerj.5809
5 downloads
43 views

Background. The fibronectin type 3 and ankyrin repeat domains 1 gene, Fank1, is an ancient, evolutionarily conserved gene present in vertebrates. Fank1-knockdown mice have oligospermia caused by an increase in apoptotic germ cells. In this study, we investigated...

["Andrology","Histology"]
doi:10.7287/peerj.preprints.27356v1
19 downloads
55 views

We argue that classic economic games and their more recent extensions should continue to play a role in fieldworkers’ methodological toolkits. Economic games are not replacements for observational and self-report studies of behavior, but rather complements to them:...

["Anthropology","Evolutionary Studies","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27355v1
22 downloads
51 views

Crowding research has become a hotbed of vision research and some fundamentals are now widely agreed upon. It is highly likely that you would agree with the following statements. 1) Bouma’s Law can be sensibly stated as saying that ‘critical distance for crowding...

["Computational Biology","Neuroscience","Anatomy and Physiology","Ophthalmology","Psychiatry and Psychology"]
doi:10.7287/peerj.preprints.27353v1
18 downloads
83 views

Aims - Biological soil crusts (BSCs) are known to affect plants’ germination and seedling establishment, but the ecological role of BSCs in more mesic climates are not so well-known. We tested the effects of moss-crusted versus uncrusted soils on seed germination...

["Ecology","Soil Science"]
doi:10.7287/peerj.preprints.27354v1
19 downloads
140 views

China consumes more than one-third of the world’s nitrogen (N) fertilizer, and an increasing amount of N fertilizer has been applied over the past decades. Although N fertilization can increase the carbon sequestration potentials of cropland in China, the quantitative...

["Agricultural Science","Soil Science","Biogeochemistry"]
doi:10.7717/peerj.5983
20 downloads
198 views

The Yongjiang river is a large, shallow, hyper-trophic, freshwater river in Guangxi, China. To investigate the presence of microcystin-RR, microcystin-LR, and microcystin-YR (MC-RR, MC-LR, and MC-YR) in the Yongjiang river and describe their correlation with environmental...

["Ecotoxicology","Environmental Impacts"]
doi:10.7717/peerj.5955
34 downloads
280 views

Infectious diseases can alter the demography of their host populations, reducing their viability even in the absence of mass mortality. Amphibians are the most threatened group of vertebrates globally, and emerging infectious diseases play a large role in their...

["Conservation Biology","Ecology","Zoology","Freshwater Biology","Population Biology"]
doi:10.7717/peerj.5949
25 downloads
217 views

Background Biocrusts, communities dominated by mosses, lichens, cyanobacteria, and other microorganisms, largely affect the carbon cycle of drylands. As poikilohydric organisms, their activity time is often limited to short hydration events. The photosynthetic...

["Ecology","Soil Science","Climate Change Biology"]
doi:10.7717/peerj.5904
67 downloads
479 views

The vertebrate fauna of the Late Cretaceous Mussentuchit Member of the Cedar Mountain Formation has been studied for nearly three decades, yet the fossil-rich unit continues to produce new information about life in western North America approximately 97 million...

["Biodiversity","Biogeography","Paleontology","Taxonomy"]
doi:10.7717/peerj.5883
22 downloads
130 views

T1 Lipase is a thermostable secretary protein of Geobacillus zalihae strain previously expressed in a prokaryotic system and purified using three-step purification: affinity 1, affinity 2, and ion exchange chromatography (IEX). This approach is time consuming and...

["Biochemistry","Computational Biology"]
doi:10.7717/peerj.5833

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