Anti-fibrotic properties of ranibizumab have been well documented. As an antagonist to Vascular Endothelial Growth Factor (VEGF), ranibizumab works by binding and neutralizes all active VEGF, thus limits the progressive cell growth and proliferation. Its application...

["Molecular Biology","Ophthalmology"]
doi:10.7287/peerj.preprints.27492v1

Corals provide structure and food sources vital for the maintenance of coral reef fish diversity. However, coral reefs are currently under threat from climate change, which has led to the largest recorded loss of live coral. The loss of live coral, and corresponding...

["Biodiversity","Ecology","Marine Biology"]
doi:10.7287/peerj.preprints.27491v1

Macronycteris commersoni (Hipposideridae), a bat species endemic to Madagascar, is widespread across the island and utilizes a range of habitat types including open woodland, degraded habitats, and forested areas from sea level to 1,325 m. Despite being widely...

["Biogeography","Evolutionary Studies"]
doi:10.7717/peerj.5866

Background Scarlet fever is recognized as being a major public health issue owing to its increase in notifications in mainland China, and an advanced response based on forecasting techniques is being adopted to tackle this. Here, we construct a new hybrid method...

["Mathematical Biology","Epidemiology","Health Policy","Infectious Diseases","Public Health"]
doi:10.7717/peerj.6165
3 downloads
3 views

Background Patients with atrial fibrillation-flutter (AF) admitted on the weekends were initially reported to have poor outcomes. The primary purpose of this study is to re-evaluate the outcomes for weekend versus weekday AF hospitalization using the 2014 Nationwide...

["Cardiology","Global Health","Health Policy"]
doi:10.7717/peerj.6211
1 download
1 view

Astelia pumila (G.Forst.) Gaudich. (Asteliaceae, Asparagales) is a major element of West Patagonian cushion peat bog vegetation. With the aim to identify appropriate chloroplast markers for the use in a phylogeographic study, the complete chloroplast genomes of...

["Biogeography","Plant Science"]
doi:10.7717/peerj.6244
1 download
1 view

Background Paddies are an important anthropogenic source of methane emissions to the atmosphere, and they are impacted by heavy metal pollution. Nickel (Ni) and cobalt (Co) pollution might either enhance or mitigate CH4 emission from paddy soils due to the total...

["Soil Science","Climate Change Biology"]
doi:10.7717/peerj.6274
1 download
1 view

Purpose The most common virus vector used in gene therapy research for ophthalmologic diseases is the adeno-associated virus (AAV) vector, which has been used successfully in a number of preclinical and clinical studies. It is important to evaluate novel AAV vectors...

["Virology","Ophthalmology"]
doi:10.7717/peerj.6317
1 download
21 views

Polyp activity in passive suspension feeders has been linked to several environmental factors such as hydrodynamics, water temperature and food concentration. To better elucidate the driving forces controlling polyp expansion in these organisms and the potential...

["Animal Behavior","Ecology","Marine Biology","Zoology"]
doi:10.7287/peerj.preprints.27490v1
13 downloads
89 views

Chrysophytes are a large group of heterotrophic, phototrophic, or even mixotrophic protists that are abundant in aquatic as well as terrestrial environments. Although much is known about chrysophyte biology and ecology, it is unknown if they are sexual or not....

["Biodiversity","Evolutionary Studies","Microbiology"]
doi:10.7717/peerj.5894
18 downloads
55 views

The fight against cancer has been a never-ending battle. Limitations of conventional therapies include lack of selectivity, poor penetration and highly toxic to the host. Using genetically modified bacteria as a tumour therapy agent has gained the interest of scientist...

["Bioengineering","Biotechnology","Microbiology","Molecular Biology","Oncology"]
doi:10.7717/peerj.5989
12 downloads
81 views

Soil physical parameter calculation by inverse modelling provides an indirect way of estimating the unsaturated hydraulic properties of soils. However many measurements are needed to provide sufficient data to determine unknown parameters. The objective of this...

["Agricultural Science","Soil Science","Environmental Impacts"]
doi:10.7717/peerj.6002
22 downloads
134 views

In Heterostegina depressa, the flagship species of laboratory investigations of larger benthic foraminifera (LBF) since the 70’s, the timing of reproduction, longevity and natural chamber building rates are still understudied. A recently developed method, the natural...

["Marine Biology","Paleontology","Population Biology"]
doi:10.7717/peerj.6096
11 downloads
53 views

Naupactus Dejean is the most diverse genus of the tribe Naupactini (Curculionidae: Entiminae), with more than 200 species occurring in South America, of which about 40 range in Argentina and neighboring countries. The Argentinean species treated herein were classified...

["Entomology","Taxonomy"]
doi:10.7717/peerj.6196
49 downloads
390 views

The recent ‘replication crisis’ in psychology has focused attention on ways of increasing methodological rigor within the behavioral sciences. Part of this work has involved promoting ‘Registered Reports’, wherein journals peer review papers prior to data collection...

["Psychiatry and Psychology","Statistics"]
doi:10.7717/peerj.6232

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