1 download
1 view

Increased levels of long noncoding RNA H19 (H19) have been observed in many inflammatory and organ fibrosis diseases including ulcerative colitis, osteoarthritis, liver fibrosis, renal fibrosis and pulmonary fibrosis. However, the role of H19 in bovine mastitis...

["Biochemistry","Cell Biology","Veterinary Medicine"]
doi:10.7717/peerj.3950

Background/Aim Strabismus is a common condition with misalignment between two eyes that may lead to decrease of visual acuity, lack of binocularity, and diplopia. It is caused by heterogeneous environmental and genetic risk factors. Our previous research has identified...

["Genetics","Genomics","Ophthalmology","Medical Genetics"]
doi:10.7717/peerj.3935

In arable cropping systems, reduced or conservation tillage practices are linked with improved soil quality, C retention and higher microbial biomass, but most long-term studies rarely focus on depths greater than 15 cm nor allow comparison of microbial community...

["Agricultural Science","Ecology","Microbiology","Soil Science"]
doi:10.7717/peerj.3930

Background Differential expression analysis on the basis of RNA-Seq count data has become a standard tool in transcriptomics. Several studies have shown that prior normalization of the data is crucial for a reliable detection of transcriptional differences. Until...

["Bioinformatics","Statistics"]
doi:10.7717/peerj.3859

Background The study objective was to investigate and synthesize available evidence relating to the psychological health of Emergency Dispatch Centre (EDC) operatives, and to identify key stressors experienced by EDC operatives. Methods Eight electronic databases...

["Emergency and Critical Care","Psychiatry and Psychology"]
doi:10.7717/peerj.3735
4 downloads
21 views

Background: Liver pathology in cats represents a frequent clinical condition occurring in animals of any age. Dietary supplementation with hepatoprotective and antioxidant products could represent a beneficial strategy to prevent and treat these disorders. We evaluated...

["Veterinary Medicine","Gastroenterology and Hepatology"]
doi:10.7287/peerj.preprints.3349v1
16 downloads
72 views

The immune system protects a host from foreign pathogens. In rare cases, the immune system can attack the cells of the host organism causing autoimmune diseases. We outline a computational framework that combines bioinformatics and network analysis with an emerging...

["Bioinformatics","Computational Biology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.3217v3
514 downloads
662 views

Choosing a model with too few parameters can involve making unrealistically simple assumptions and lead to high bias, poor prediction, and missed opportunities for insight. Such models are not flexible enough to describe the sample or the population well. A model...

["Statistics"]
doi:10.7287/peerj.preprints.1103v3
8 downloads
279 views

To satisfy the high timber demands of human society, forest plantations, especially with fast growing species like pines and eucalypts, are increasing worldwide. In some European countries, the number of wildfires has been augmenting since the second half of the...

["Natural Resource Management"]
doi:10.7287/peerj.preprints.3348v1
383 downloads
523 views

Pattern recognition is commonly used for identifying an unknown entity from a set of known objects curated in a database, and find use in various applications such as fingerprint matching and microbial identification. Mass spectrometry is increasingly used in identifying...

["Biodiversity","Bioinformatics","Ecology","Microbiology","Science and Medical Education"]
doi:10.7287/peerj.preprints.580v3
13 downloads
262 views

Lakes are dynamic and complex ecosystems that can be influenced by physical, chemical, and biological processes. Additionally, individual lakes are often chemically and physically distinct, even within the same geographic region. Here we show that differences in...

["Biodiversity","Ecology","Environmental Sciences","Microbiology","Freshwater Biology"]
doi:10.7717/peerj.3937
11 downloads
112 views

Plant resistance against insect herbivory has greatly focused on antibiosis, whereby the plant has a deleterious effect on the herbivore, and antixenosis, whereby the plant is able to direct the herbivore away from it. Although these two types of resistance may...

["Agricultural Science","Entomology","Plant Science"]
doi:10.7717/peerj.3934
3 downloads
83 views

Background Software maintenance is an important activity in the development process where maintenance team members leave and new members join over time. The identification of files which are changed together frequently has been proposed several times. Yet, existing...

["Data Science","Software Engineering"]
doi:10.7717/peerj-cs.135
7 downloads
84 views

Background The present study investigated differences in reading and spelling outcomes in Dutch and English as a second language (ESL) in adolescents with a high familial risk of dyslexia, of whom some have developed dyslexia (HRDys) while others have not (HRnonDys),...

["Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.3895
9 downloads
388 views

Background Dual energy X-ray absorptiometry (DXA) is a commonly used instrument for analysing segmental body composition (BC). The information from the scan guides the clinician in the treatment of conditions such as obesity and can be used to monitor recovery...

["Drugs and Devices","Epidemiology","Kinesiology","Nutrition","Radiology and Medical Imaging"]
doi:10.7717/peerj.3880

Top subject areas - Articles & Preprints

Top subject areas - People

View all subject areas