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This paper reports an integrated solution, called BALSA, for the secondary analysis of next generation sequencing data; it exploits the computational power of GPU and an intricate memory management to give a fast and accurate analysis. From raw reads to variants...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]

The neXtProt database is a comprehensive knowledge platform recently adopted by the Chromosome-centric Human Proteome Project as the main reference database. The primary goal of the project is to identify and catalog every human protein encoded in the human genome....

["Bioinformatics","Computational Biology"]

Effects of the antimicrobial agent triclosan to natural periphyton communities (biofilms, comprising primarily microalgae and bacteria) were assessed in two independent experiments during spring and summer. For that purpose a semi-static test system was used in...

["Ecology","Marine Biology","Microbiology","Toxicology"]

Diffusion-weighted Magnetic Resonance Imaging (DW-MRI) has emerged as the most popular neuroimaging technique used to depict the biological microstructural properties of human brain white matter. However, like other MRI techniques, traditional DW-MRI data remains...

["Neurology","Radiology and Medical Imaging"]

Because microorganisms are sensitive to temperature, ongoing global warming is predicted to influence microbial community structure and function. We used large-scale warming experiments established at two sites near the northern and southern boundaries of US eastern...


Background: The individual running style has an impact on the running performance as well as the running injury risk. In order to increase the performance and lower the injury risk, runners should be educated towards a healthy running style. But before advices...

["Bioinformatics","Anatomy and Physiology","Orthopedics","Computational Science"]

Aim. To determine the characteristics of megajournal authors, the nature of the manuscripts they are submitting to these journals, factors influencing their decision to publish in a megajournal, sources of funding for article processing charges (APCs) or other...

["Science Policy"]

Comparing risks among pesticides has substantial utility for decision makers. However, if rating schemes to compare risks are to be used, they must be conceptually and mathematically sound. We address limitations with pesticide risk rating schemes by examining...

["Agricultural Science","Entomology","Environmental Sciences","Toxicology"]

How do humans see three-dimensional shape based on two-dimensional shading? Much research has assumed that a ‘light from above’ bias solves the ambiguity of shape from shading. Counter to the ‘light from above’ bias, studies of Bayesian priors have found that such...

["Neuroscience","Psychiatry and Psychology","Human\u2013Computer Interaction"]

The resolution of rapid evolutionary radiations or “bushes” in the tree of life has been one of the most difficult and interesting problems in phylogenetics. The avian order Galliformes appears to have undergone several rapid radiations that have limited the resolution...

["Evolutionary Studies","Taxonomy","Zoology"]

Background. Previous research has supported gender-specific aetiological factors in oppositional defiant disorder (ODD) and conduct disorder (CD). The aims of this study were to identify gender-specific associations between the behavioural problems–ODD/CD-like...

["Genetics","Epidemiology","Psychiatry and Psychology"]

Purpose. To design and validate a prenatal chromosomal microarray testing strategy that moves away from size-based detection thresholds, towards a more clinically relevant analysis, providing higher resolution than G-banded chromosomes but avoiding the detection...

["Genetics","Medical Genetics","Ethical Issues"]

Background: Illicit drug use influences people’s lives and elicits unwanted here is an increase in young people’s drug use in Sweden. This study aimed to investigate Swedish high-school pupils’ attitudes, impulsiveness and gender differences linked to drug use....

["Drugs and Devices","Psychiatry and Psychology"]

The role of soil organic carbon (SOC) in maintaining soil conditions and its resulting services is well established. Currently, over 1,000 articles per year are being published in peer-reviewed journals, and increasing at about 10% per year. It was not until the...

["Agricultural Science","Ecology","Environmental Sciences","Soil Science","Science Policy"]

Amplifiers are signals that improve the perception of underlying differences in quality. They are cost free and advantageous to high quality individuals, but disadvantageous to low quality individuals, as poor quality is easier perceived because of the amplifier....

["Animal Behavior","Anthropology","Evolutionary Studies","Zoology"]

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