Peer-reviewed Articles

Maximakinin (MK), an amphibian peptide possessing the C-terminal sequence of bradykinin (BK), is a BK B2 receptor (B2R) agonist eliciting prolonged signaling. We reinvestigated this 19-mer for species-specific pharmacologic profile, in vivo confirmation of resistance...

["Cardiology","Pharmacology"]
doi:10.7717/peerj.2911

Wild tomatoes are a valuable source of disease resistance germplasm for tomato (Solanum lycopersicum) breeders. Many species are known to possess a certain degree of resistance against certain pathogens; however, evolution of resistance traits is yet poorly understood....

["Ecology","Evolutionary Studies","Plant Science"]
doi:10.7717/peerj.2910

Azhdarchid pterosaurs include the largest animals to ever take to the skies with some species exceeding 10 metres in wingspan and 220 kg in mass. Associated skeletons show that azhdarchids were long-necked, long-jawed predators that combined a wing planform suited...

["Paleontology","Zoology"]
doi:10.7717/peerj.2908

Type I restriction-modification enzymes are multisubunit, multifunctional molecular machines that recognize specific DNA target sequences, and their multisubunit organization underlies their multifunctionality. EcoR124I is the archetype of Type I restriction-modification...

["Biochemistry","Biophysics","Computational Biology","Molecular Biology"]
doi:10.7717/peerj.2887

We present the first study that evaluates jaguar-puma interactions in the arid lands of northern Mexico, where jaguars have their northernmost breeding population and both predators are persecuted for livestock depredation. We tested whether jaguars are the dominant...

["Conservation Biology","Ecology","Zoology"]
doi:10.7717/peerj.2886

Future demands for increased food production are expected to have severe impacts on prairie biodiversity and ecosystem integrity. Prairie avifauna of North America have experienced drastic population declines, prompting numerous conservation efforts, which have...

["Biogeography","Conservation Biology","Ecology"]
doi:10.7717/peerj.2879

Foot problems are a major cause of morbidity and mortality in elephants, but are underreported due to difficulties in diagnosis, particularly of conditions affecting the bones and internal structures. Here we evaluate post-mortem computer tomographic (CT) scans...

["Veterinary Medicine","Pathology","Radiology and Medical Imaging"]
doi:10.7717/peerj.2877

Background Platinum-based agents are widely used in chemotherapy against solid tumors and insufficient intracellular drug accumulation is one of the leading causes of platinum resistance which is associated with poor survival of tumor patients. Thus, the detection...

["Cell Biology","Drugs and Devices","Oncology"]
doi:10.7717/peerj.2873

Dongsha Atoll (also known as Pratas) in Taiwan is the northernmost atoll in the South China Sea and a designated marine national park since 2007. The marine park’s scope of protection covers the bio-resources of its waters in addition to uplands, so it is important...

["Ecology","Environmental Sciences","Marine Biology"]
doi:10.7717/peerj.2871
23 downloads
140 views

Background The shells of molluscs survive well in many sedimentary contexts and yield information about the diet of prehistoric humans. They also yield evidence of symbolic behaviours through their use as beads for body adornments. Researchers often analyse the...

["Ecology","Marine Biology","Paleontology","Zoology"]
doi:10.7717/peerj.2903
14 downloads
95 views

The successful navigation of social interactions depends on a range of cognitive faculties—including the ability to achieve joint attention with others to share information and experiences. We investigated the influence that intention monitoring processes have...

["Neuroscience","Cognitive Disorders","Human-Computer Interaction"]
doi:10.7717/peerj.2899
13 downloads
86 views

The effect of aging on the process of word encoding for fixated words and words presented to the right of the fixation point during the reading of sentences in Chinese was investigated with two disappearing text experiments. The results of Experiment 1 showed that...

["Cognitive Disorders","Ophthalmology","Psychiatry and Psychology"]
doi:10.7717/peerj.2897
12 downloads
179 views

Autophagy serves as a turnover mechanism for the recycling of redundant and/or damaged macromolecules present in eukaryotic cells to re-use them under starvation conditions via a double-membrane structure known as autophagosome. A set of eukaryotic genes called...

["Bioinformatics","Cell Biology","Computational Biology"]
doi:10.7717/peerj.2878
17 downloads
98 views

Background Psychological disorders are common in diabetes mellitus (DM) patients, and the aim of this study was to estimate the prevalence of psychological distress and to determine the influence factors associated with psychological distress among DM patients...

["Diabetes and Endocrinology","Epidemiology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.2869
16 downloads
55 views

The biological potential of Vip and Cry proteins from Bacillus is well known and widely established. Thus, it is important to look for new genes showing different modes of action, selecting those with differentiated entomotoxic activity against Diatraea flavipennella...

["Agricultural Science","Biotechnology","Entomology","Genetics"]
doi:10.7717/peerj.2866

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