Peer-reviewed Articles

150 downloads
819 views

Sorting nexin-1 (SNX1) is an important functional protein in cell endocytosis, efflux, protein sorting, cell signal transduction, etc; however, the expression, the role and clinical relevance of SNX1 have not been investigated in gastric cancer (GC). In this study,...

["Gastroenterology and Hepatology","Oncology","Histology"]
doi:10.7717/peerj.4829
3 citations
511 downloads
1,940 views

Cancer progression is a polygenic procedure in which the exosomes can function as substantial roles. Exosomes are tiny, phospholipid bilayer membrane nanovesicles of endocytic derivation with a diameter of 40–100 nm. These nanovesicles can transport bioactive molecules...

["Genetics","Oncology"]
doi:10.7717/peerj.4763
1 citation
147 downloads
594 views

Objectives The prognosis of people with pancreatic cancer is extremely unfavorable. However, the prognostic factors remain largely undefined. We aimed to perform comprehensive analyses of clinicopathologic characteristics, laboratory parameters, and treatment protocols...

["Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.4893
2 citations
280 downloads
880 views

Background Breast cancer stem cells (BCSCs) are associated with the invasion of breast cancer. In recent years, studies have demonstrated different phenotypes among BCSCs. Furthermore, BCSCs of diverse phenotypes are present at different tumour sites and different...

["Cell Biology","Oncology"]
doi:10.7717/peerj.4805
2 citations
242 downloads
1,113 views

Background Using DNA microarrays, we previously identified 451 genes expressed in 19 different human tissues. Although ubiquitously expressed, the variable expression patterns of these “housekeeping genes” (HKGs) could separate one normal human tissue type from...

["Bioinformatics","Computational Biology","Genomics","Oncology","Medical Genetics"]
doi:10.7717/peerj.4719
3 citations
398 downloads
1,311 views

Background Gastric cancer (GC) is one of the most common cancers with high mortality globally. However, the molecular mechanisms of GC are unclear, and the prognosis of GC is poor. Therefore, it is important to explore the underlying mechanisms and screen for novel...

["Bioinformatics","Genetics","Oncology"]
doi:10.7717/peerj.4692
1 citation
179 downloads
832 views

In 2015, as part of the Prostate Cancer Foundation–Movember Foundation Reproducibility Initiative, we published a Registered Report (Shan et al., 2015) that described how we intended to replicate selected experiments from the paper “Androgen Receptor Splice Variants...

["Cell Biology","Oncology"]
doi:10.7717/peerj.4661
1 citation
239 downloads
1,444 views

Objective A subgroup of parents of children who have been treated for childhood cancer report high levels of psychological distress. To date there is no empirically supported psychological treatment targeting cancer-related psychological distress in this population....

["Clinical Trials","Oncology","Pediatrics","Psychiatry and Psychology"]
doi:10.7717/peerj.4570
1 citation
257 downloads
1,381 views

Background The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life. Here we aim to examine the expression profiles of transient...

["Molecular Biology","Neuroscience","Anesthesiology and Pain Management","Oncology","Pharmacology"]
doi:10.7717/peerj.4622
3 citations
246 downloads
971 views

Prolonged life expectancy in humans has been accompanied by an increase in the prevalence of cancers. Breast cancer (BC) is the leading cause of cancer-related deaths. It accounts for one-fourth of all diagnosed cancers and affects one in eight females worldwide....

["Oncology","Data Mining and Machine Learning"]
doi:10.7717/peerj.4551
1 citation
190 downloads
1,054 views

Background We established a glioma biobank at Beijing Tiantan Hospital in November, 2010. Specialized residents have been trained to collect, store and manage the biobank in accordance with standard operating procedures. Methods One hundred samples were selected...

["Neurology","Oncology","Translational Medicine"]
doi:10.7717/peerj.4450
1 citation
197 downloads
1,444 views

Background Poor nutritional status among patients with advanced stage head and neck squamous cell carcinoma (HNSCC) is common. Albumin is a common indicator of nutritional status and has been shown to be a predictor of oncological outcomes and perioperative morbidity....

["Oncology","Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4490
1 citation
146 downloads
1,282 views

Background Tumor-induced angiogenesis is an imperative event in pledging new vasculature for tumor metastasis. Since overexpression of neuronal proteins gamma-synuclein (γ-Syn) and cellular prion protein (PrPC) is always detected in advanced stages of cancer diseases...

["Biochemistry","Biotechnology","Cell Biology","Molecular Biology","Oncology"]
doi:10.7717/peerj.4506
1 citation
224 downloads
1,422 views

Background Advanced treatment of oral cancer increases survival rates; however, it also increases the risk of developing shoulder dysfunction, dysphagia, oral dysfunction, donor site morbidity and psychological issues. This single-arm preliminary pilot study aims...

["Clinical Trials","Evidence Based Medicine","Oncology"]
doi:10.7717/peerj.4419
258 downloads
1,448 views

Triple negative breast cancer (TNBC) is a belligerent carcinoma that is unresponsive to targeted receptor therapies. Development of new treatment strategies would benefit from an expanded repertoire of in vitro cell culture systems, such as those that support tridimensional...

["Cell Biology","Anatomy and Physiology","Oncology","Pathology","Histology"]
doi:10.7717/peerj.4340

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