Peer-reviewed Articles

121 downloads
385 views

Ovarian cancer (OC) is the second most common gynecologic malignancy. A clinical observational study was performed to investigate whether indicators that assess the risk of metastasis can identify recurrence earlier in OC patients. By successfully recruiting 41...

["Gynecology and Obstetrics","Oncology"]
doi:10.7717/peerj.5912
97 downloads
370 views

Colorectal cancer ranks third among the most commonly diagnosed cancers in the United States. Current therapies have a range of side effects, and the development of a reliable animal model to speed the discovery of safe effective preventative therapies would be...

["Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5602
150 downloads
587 views

Aim Anaplastic thyroid carcinoma (ATC) is the most lethal thyroid malignancy. Identification of novel drug targets is urgently needed. Materials & Methods We re-analyzed several GEO datasets by systematic retrieval and data merging. Differentially expressed genes...

["Genetics","Diabetes and Endocrinology","Oncology"]
doi:10.7717/peerj.5822
95 downloads
331 views

Objective To investigate the interaction of non-coding RNAs (ncRNAs) in hepatocellular carcinoma. Methods We compared the ncRNAs and mRNAs expression profiles of hepatocellular carcinoma and adjacent tissue by microarray and RT-PCR. The relationship between different...

["Gastroenterology and Hepatology","Oncology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.5787
90 downloads
328 views

Background Oxidative stress (OS) is a key characteristic feature in cancer initiation and progression. Among multiple cancers, NADPH oxidase (NOX) dependent free radical production is implicated in oxidative stress. P22phox, a subunit of NADPH oxidase encoded by...

["Genetics","Oncology","Medical Genetics"]
doi:10.7717/peerj.5509
161 downloads
536 views

Background Acetylsalicylic acid was renamed aspirin in 1899, and it has been widely used for its multiple biological actions. Because of the diversity of the cellular processes and diseases that aspirin reportedly affects and benefits, uncertainty remains regarding...

["Bioinformatics","Drugs and Devices","Oncology"]
doi:10.7717/peerj.5667
1 citation
105 downloads
351 views

Introduction The present study investigated the crucial role of inflammation-based prognostic scores in locally advanced cervical esophageal squamous cell carcinoma (ESCC) patients who underwent curative concurrent chemoradiotherapy (CCRT). Methods There were 411...

["Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5655
1 citation
246 downloads
796 views

Cervical cancer is the fourth most common cancer in women worldwide with human papillomavirus (HPV) being the main cause the disease. Chromosomal amplifications have been identified as a source of upregulation for cervical cancer driver genes but cannot fully explain...

["Computational Biology","Microbiology","Oncology"]
doi:10.7717/peerj.5590
106 downloads
391 views

Purpose Most studies on neuroblastoma (NB) have been conducted in Western countries or Japan. The objective of our study was to analyze clinical and pathological features, MYCN status, surgical methods, and prognosis in Chinese NB patients. Methods A retrospective,...

["Oncology","Pediatrics","Surgery and Surgical Specialties"]
doi:10.7717/peerj.5665
112 downloads
897 views

Objectives The five-year survival rate of head and neck cancer (HNC) after radiotherapy (RT) varies widely from 35% to 89%. Many studies have addressed the effect of socioeconomic status and urban dwelling on the survival of HNC, but a limited number of studies...

["Dentistry","Oncology","Otorhinolaryngology","Public Health"]
doi:10.7717/peerj.5591
1 citation
89 downloads
408 views

Combination Index (CI) analysis suggested that MBIC and doxorubicin synergistically inhibited up to 97% of cell proliferation in ER+/PR+MCF-7 and triple negative MDA-MB-231 breast cancer cell lines. Moreover, treatment of the breast cancer cells with the combined...

["Cell Biology","Oncology"]
doi:10.7717/peerj.5577
102 downloads
402 views

Background Abnormal methylation of TNFRSF10C was found to be associated with different types of cancers, excluding colorectal cancer (CRC). In this paper, the performance of TNFRSF10C methylation in CRC was studied in two stages. Method The discovery stage was...

["Biochemistry","Genetics","Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5336
168 downloads
531 views

Objective The mechanism underlying colon cancer metastasis remain unclear. This study aimed to elucidate the genes alteration during the metastasis of colon cancer and identify genes that crucial to the metastasis and survival of colon cancer patients. Methods...

["Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5433
1 citation
420 downloads
1,180 views

Objectives To comprehensively analyse the global scientific outputs of hepatocellular carcinoma (HCC) research. Methods Data of publications were downloaded from the Web of Science Core Collection. We used CiteSpace IV and Excel 2016 to analyse literature information,...

["Gastroenterology and Hepatology","Oncology","Statistics"]
doi:10.7717/peerj.5477

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