Peer-reviewed Articles

79 downloads
182 views

Background The hepatic microenvironment, which may include chronic inflammation and fibrosis, is considered to contribute to the development of liver metastases. Hepatic steatosis (HS) might cause liver inflammation and fibrosis. However, to date, no studies have...

["Epidemiology","Evidence Based Medicine","Oncology"]
doi:10.7717/peerj.6612
1 citation
302 downloads
2,029 views

Introduction The treatment with tyrosine kinase inhibitors (TKIs) has drastically improved the outcome of chronic myeloid leukemia (CML) patients. This study was conducted to examine the risk of secondary cancers (SCs) in the CML patients who were diagnosed and...

["Epidemiology","Internal Medicine","Oncology"]
doi:10.7717/peerj.4342
1 citation
178 downloads
1,195 views

Background Pituitary adenoma is one of the most common intracranial neoplasms, and its primary treatment is endoscopic endonasal transsphenoidal tumorectomy. Postoperative hypokalemia in these patients is a common complication, and is associated with morbidity...

["Diabetes and Endocrinology","Epidemiology","Oncology"]
doi:10.7717/peerj.3337
4 citations
209 downloads
1,221 views

The incidence of cutaneous melanoma (CM) has rapidly increased over the past four decades. CM is often overlooked in East Asian populations due to its low incidence, despite East Asia making up 22% of the world’s population. Since the 1990s, Caucasian populations...

["Dermatology","Epidemiology","Oncology","Public Health"]
doi:10.7717/peerj.2809
1 citation
427 downloads
1,385 views

This large-scale, controlled cohort study estimated the risks of lung cancer in patients with gastro-esophageal reflux disease (GERD) in Taiwan. We conducted this population-based study using data from the National Health Insurance Research Database of Taiwan during...

["Epidemiology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.2753
10 citations
498 downloads
1,987 views

MicroRNAs (miRNAs) may promote the development and progression of human cancers. Therefore, components of the miRNA biogenesis pathway may play critical roles in human cancer. Single nucleotide polymorphisms (SNPs) or mutations in genes involved in the miRNA biogenesis...

["Genetics","Epidemiology","Evidence Based Medicine","Oncology"]
doi:10.7717/peerj.2706
2 citations
287 downloads
1,386 views

Background Cancer research is a national and international priority, with the efficiency and effectiveness of current anti-tumor therapies being one of the major challenges with which physicians are faced. Objective To assess the impact of exposure to tobacco smoke,...

["Epidemiology","Gynecology and Obstetrics","Oncology","Public Health","Women's Health"]
doi:10.7717/peerj.2448
4 citations
330 downloads
1,606 views

Background. Adenomatous polyposis coli (APC) is widely known as an antagonist of the Wnt signaling pathway via the inactivation of β-catenin. An increasing number of studies have reported that APC methylation contributes to the predisposition to breast cancer (BC)....

["Epidemiology","Genetics","Oncology","Women's Health"]
doi:10.7717/peerj.2203
12 citations
1,569 downloads
19,649 views

The level of atmospheric oxygen, a driver of free radical damage and tumorigenesis, decreases sharply with rising elevation. To understand whether ambient oxygen plays a role in human carcinogenesis, we characterized age-adjusted cancer incidence (compiled by the...

["Epidemiology","Oncology","Public Health","Respiratory Medicine","Statistics"]
doi:10.7717/peerj.705

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