Peer-reviewed Articles

18 downloads
108 views

Background Marfan syndrome (MFS) is an inherited connective tissue disorder affecting the ocular, skeletal and cardiovascular systems. Previous studies of MFS have demonstrated the association between genetic defects and clinical manifestations. Our purpose was...

["Genetics","Genomics","Molecular Biology","Cardiology","Medical Genetics"]
doi:10.7717/peerj.5927
81 downloads
588 views

Congenital heart disease (CHD) affects a considerable number of children and adults worldwide. This implicates not only developmental disorders, high mortality, and reduced quality of life but also, high costs for the healthcare systems. CHD refers to a variety...

["Cell Biology","Developmental Biology","Anatomy and Physiology","Cardiology","Pathology"]
doi:10.7717/peerj.5805
462 downloads
451 views

Background The aim of the study was to assess the effects of walking on the blood pressure in sedentary adults with differing degrees of systolic blood pressure (SBP). Methods A total of 529 subjects with SBP above 120 mmHg were enrolled. Blood pressure, body weight,...

["Cardiology","Internal Medicine","Public Health"]
doi:10.7717/peerj.5471
75 downloads
308 views

Background The use of an implantable cardioverter-defibrillator (ICD) has been established as an effective secondary prevention strategy for ventricular tachycardia (VT)/ventricular fibrillation (VF). However, few reports discuss the difference in clinical predictors...

["Cardiology"]
doi:10.7717/peerj.5312
91 downloads
287 views

Objective MicroRNA (miR)-122 is highly expressed in the liver, where it has been implicated as a regulator of fatty-acid metabolism. A recent study reported that miR-122 plays a role in pathogenesis of atherosclerosis; however, whether it connects with severity...

["Cardiology","Geriatrics"]
doi:10.7717/peerj.5218
1 citation
92 downloads
303 views

Introduction Chronic total occlusion (CTO) is common in the presence of other significantly narrowed coronary arteries. The impact of total occlusion and its association with completeness of revascularization on patients with multivessel disease undergoing coronary...

["Cardiology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4909
81 downloads
479 views

Background Minimally invasive mitral valve surgery (MVS) via right mini-thoracotomy has recently attracted a lot of attention. Minimally invasive MVS shows postoperative results that are comparable to those of conventional MVS through the median sternotomy as per...

["Cardiology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4810
103 downloads
481 views

Occlusive artery disease (CAD) is the leading cause of death worldwide. Bypass graft surgery remains the most prevalently performed treatment for occlusive arterial disease, and veins are the most frequently used conduits for surgical revascularization. However,...

["Bioinformatics","Cell Biology","Genetics","Genomics","Cardiology"]
doi:10.7717/peerj.4704
151 downloads
521 views

Background Good results of drug-eluting balloon (DEB) use are achieved in in-stent restenosis (ISR) lesions, small vessel disease, long lesions, and bifurcations. However, few reports exist about DEB use in acute myocardial infarction (AMI) with ISR. This study’s...

["Cardiology"]
doi:10.7717/peerj.4646
128 downloads
757 views

Background Kawasaki disease (KD) is an immune-mediated systemic vasculitis, and infection plays an important role in the pathophysiology of KD. The susceptibility to infectious disease in patients with KD remains largely unclear. This study aimed to investigate...

["Allergy and Clinical Immunology","Cardiology","Immunology","Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.4539
192 downloads
1,026 views

Background Patients with acute myocardial infarction (AMI) and bundle-branch block have poor prognoses. The new European Society of Cardiology guideline suggests a primary percutaneous coronary intervention strategy when persistent ischemic symptoms occur in patients...

["Cardiology"]
doi:10.7717/peerj.4497
206 downloads
1,761 views

RNA editing modifies transcripts and may alter their regulation or function. In humans, the most common modification is adenosine to inosine (A-to-I). We examined the global characteristics of RNA editing in 4,301 human tissue samples. More than 1.6 million A-to-I...

["Computational Biology","Genetics","Genomics","Cardiology","Computational Science"]
doi:10.7717/peerj.4466
146 downloads
1,104 views

Objectives To assess and compare the predictive ability of three risk evaluation systems (SinoSCORE, EuroSCORE II and the STS risk evaluation system) in patients aged ≥70, and who underwent coronary artery bypass grafting (CABG) in East China. Methods Three risk...

["Cardiology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.4413
308 downloads
1,151 views

Background Although several studies have identified risk factors for high blood pressure (BP), data from Afro-Caribbean populations are limited. Additionally, less is known about how putative risk factors operate in young adults and how social factors influence...

["Cardiology","Epidemiology","Global Health","Internal Medicine","Public Health"]
doi:10.7717/peerj.4385
397 downloads
1,450 views

Objectives We aimed to evaluate the global scientific output of gene research of myocardial infarction and explore their hotspots and frontiers from 2001 to 2015, using bibliometric methods. Methods Articles about the gene research of myocardial infarction between...

["Genetics","Cardiology","Statistics","Medical Genetics"]
doi:10.7717/peerj.4354

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