536 downloads
1,164 views

The integrity of science requires that the process be based on sound experimental design and objective methodology. Strategies that increase reproducibility and transparency in science protect this integrity by reducing conscious and unconscious biases. Given the...

["Evolutionary Studies","Ethical Issues"]
doi:10.7287/peerj.preprints.26585v4
37 downloads
136 views

Background. A number of recent high-profile cases have focused attention on scientific misconduct and other problematic issues with the peer review process. The retraction of journal publications is an important part of the scientific publishing process that serves...

["Bioinformatics","Oncology","Ethical Issues","Science Policy"]
doi:10.7287/peerj.preprints.27427v1
48 downloads
104 views

Treatment of head louse infestation has evolved from widespread use of neurotoxic insecticides that have been extensively affected by resistance since the mid-1990s into the use of so-called physically acting treatments. It is widely believed that physically acting...

["Health Policy","Infectious Diseases","Pharmacology","Public Health","Ethical Issues"]
doi:10.7287/peerj.preprints.27412v1
74 downloads
103 views

Psychiatric disorders present distinct clinical challenges which are partly attributable to their multifactorial aetiology and the absence of laboratory tests that can be used to confirm diagnosis or predict risk. Psychiatric disorders are highly heritable, but...

["Genetics","Genomics","Ethical Issues","Medical Genetics"]
doi:10.7287/peerj.preprints.27392v1
98 downloads
646 views

Background Captive cetacean attractions are growing in number globally, their operators citing entertainment, education, and conservation as benefits. Those for and against developing such attractions claim public support. Previous public opinion research, however,...

["Conservation Biology","Ethical Issues","Science Policy","Natural Resource Management"]
doi:10.7717/peerj.5953
1,570 downloads
3,587 views

This article proposes quantitative answers to meta-scientific questions including "how much knowledge is attained by a research field?","how rapidly is a field making progress?", "what is the expected reproducibility of a result?", "how much knowledge is lost from...

["Computational Biology","Ethical Issues","Science Policy","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.1968v5
300 downloads
740 views

Publications in reputed peer reviewed journals are often looked upon as tenets on which future scientific thought is built. Sometimes published information can be flawed and errors in published research should be expediently reported, preferably by a peer review...

["Conservation Biology","Ecology","Ethical Issues","Natural Resource Management","Population Biology"]
doi:10.7287/peerj.preprints.27349v1
563 downloads
978 views

Using the term "Open data" has become a bit of a fashion, but using it without clear specifications is misleading i.e. it can be considered just an empty phrase. Probably even worse is the term "Open Science" — can science be NOT open at all? Are we reinventing...

["Ethical Issues","Legal Issues","Science Policy","Spatial and Geographic Information Science"]
doi:10.7287/peerj.preprints.27127v2
118 downloads
207 views

The 21st century will undeniably represent a major turn in the development of human societies, as Earth’s limiting resources can no longer support the current pace of material consumption (supplemental file S1). In this context, Ripple et al. (2017) identified...

["Agricultural Science","Biodiversity","Ethical Issues","Natural Resource Management","Environmental Impacts"]
doi:10.7287/peerj.preprints.27276v1
97 downloads
1,053 views

Background Medical decision-making is difficult when information is limited due to its rareness. For example, there are two treatment options for patients affected by a rare disease with high lethality. The information about both treatment effects is unavailable...

["Bioinformatics","Clinical Trials","Public Health","Ethical Issues","Statistics"]
doi:10.7717/peerj.5677
64 downloads
137 views

Background: Medical decision-making is difficult when information is limited due to rareness. For example, there are two treatment options for patients affected by a rare disease with high lethality. The information about both treatment effects is unavailable or...

["Bioinformatics","Clinical Trials","Public Health","Ethical Issues","Statistics"]
doi:10.7287/peerj.preprints.27170v1
160 downloads
482 views

The success of personalized medicine does not only rely on methodological advances but also on the availability of data to learn from. While the generation and sharing of large data sets is becoming increasingly easier, there is a remarkable lack of diversity within...

["Genomics","Neuroscience","Ethical Issues","Data Mining and Machine Learning","Data Science"]
doi:10.7287/peerj.preprints.27079v1
148 downloads
597 views

Background Angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARB) are the most commonly prescribed antihypertensive medications in higher-risk surgical patients. However, there is no clinical consensus on their use in the perioperative...

["Anesthesiology and Pain Management","Surgery and Surgical Specialties","Ethical Issues"]
doi:10.7717/peerj.5061
640 downloads
1,239 views

Authorship of publications is the main way scientists received credit for their academic research. But as scientific research projects have become larger and more collaborative, the number of contributors has increased, and so has the potential for disputes over...

["Ethical Issues","Legal Issues","Science Policy"]
doi:10.7287/peerj.preprints.26987v1
3,666 downloads
7,260 views

Scientific publications have not traditionally been accompanied by data, either during the peer review process or when published. Concern has arisen that the literature in many fields may contain inaccuracies or errors that cannot be detected without inspecting...

["Ethical Issues","Science and Medical Education","Statistics"]
doi:10.7287/peerj.preprints.26968v1

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