44 downloads
120 views

This detailed analysis provides an insight into aging processes in the human organism. The developmental program that controls the regulation of gene expression through epigenetic modifications leads to cellular senescence in the latter life. This epigenetic development...

["Cell Biology","Developmental Biology","Genetics","Molecular Biology"]
doi:10.7287/peerj.preprints.26998v1
48 downloads
375 views

Morphogenetic movements during embryogenesis require dynamic changes in epithelial cell polarity and cytoskeletal reorganization. Such changes involve, among others, rearrangements of cell-cell contacts and protein traffic. In Drosophila melanogaster, neuroblast...

["Developmental Biology","Genetics"]
doi:10.7717/peerj.5042
42 downloads
283 views

Background Aflatoxin B1 (AFB1), deoxynivalenol (DON), HT-2, ochratoxin A (OTA), zearalenone (ZEA) are the most common mycotoxins that are found in corn-based animal feed which have multiple toxic effects on animals and humans. Previous studies reported that these...

["Agricultural Science","Cell Biology","Developmental Biology","Food Science and Technology","Toxicology"]
doi:10.7717/peerj.5111
45 downloads
303 views

RNA interference (RNAi) technology may be useful for developing new crop protection strategies against the soybean pod borer (SPB; Leguminivora glycinivorella), which is a critical soybean pest in northeastern Asia. Immune-related genes have been recently identified...

["Agricultural Science","Developmental Biology","Entomology"]
doi:10.7717/peerj.4931
136 downloads
787 views

The patterns of bone modeling and mineral mobilization (skeletal homeostasis) among mammals other than humans and laboratory rodents are still poorly known. In this study we assessed the pattern of bone formation and bone resorption in the femur of a wild population...

["Developmental Biology","Evolutionary Studies","Zoology","Anatomy and Physiology","Histology"]
doi:10.7717/peerj.4944
73 downloads
646 views

Although comparative studies of anuran ontogeny have provided new data on heterochrony in the life cycles of frogs, most of them have not included ossification sequences. Using differential staining techniques, we observe and describe differences and similarities...

["Biodiversity","Developmental Biology","Evolutionary Studies","Taxonomy","Zoology"]
doi:10.7717/peerj.4525
61 downloads
320 views

Lesion of the dopaminergic neurons of the nigrostriatal system is a key feature of Parkinson’s disease (PD). Alpha-synuclein is a protein that is a major component of Lewy bodies, histopathological hallmarks of PD, and is involved in regulation of dopamine (DA)...

["Developmental Biology","Neuroscience","Neurology","Pathology"]
doi:10.7717/peerj.4779
66 downloads
170 views

RNA interference (RNAi) technology may be useful for developing new crop protection strategies against the soybean pod borer (SPB; Leguminivora glycinivorella), which is a critical soybean pest in northeastern Asia. Immune-related genes have been recently identified...

["Agricultural Science","Developmental Biology","Entomology"]
doi:10.7287/peerj.preprints.26923v2
235 downloads
1,312 views

The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was heralded as a major breakthrough of the decade in stem cell research. The ability to reprogram human somatic cells to a pluripotent embryonic stem cell-like state through the...

["Cell Biology","Developmental Biology","Genetics"]
doi:10.7717/peerj.4370
221 downloads
528 views

Lesion of the dopaminergic neurons of the nigrostriatal system is a key feature of Parkinson's disease (PD). Alpha-synuclein is a protein that is a major component of Lewy bodies, histopathological hallmarks of PD, and is involved in regulation of dopamine (DA)...

["Developmental Biology","Neuroscience","Neurology","Pathology"]
doi:10.7287/peerj.preprints.26547v2
56 downloads
353 views

Asymmetries in the maternal behaviour and anatomy might play an important role in the development of primate manual lateralization. In particular, early life asymmetries in mother’s and infant’s behaviour have been suggested to be associated with the development...

["Animal Behavior","Developmental Biology","Ecology","Evolutionary Studies","Neuroscience"]
doi:10.7717/peerj.4736
163 downloads
232 views

Fish are sensitive to temperature, but the intergenerational consequences of maternal exposure to high temperature on offspring adaptive behaviour and underlying mechanisms are unknown. Here we show that a thermal maternal stress induces emotional and cognitive...

["Animal Behavior","Aquaculture, Fisheries and Fish Science","Developmental Biology","Genomics","Climate Change Biology"]
doi:10.7287/peerj.preprints.26910v1
132 downloads
530 views

Background Freemartinism generally occurs in female offspring of dizygotic twins in a mixed-sex pregnancy. Most bovine heterosexual twin females are freemartins. However, about 10% of bovine heterosexual twin females are fertile. Farmers mostly cull bovine fertile...

["Agricultural Science","Developmental Biology","Veterinary Medicine","Zoology"]
doi:10.7717/peerj.4616
97 downloads
418 views

Background The hatch window that varies from 24 to 48 h is known to influence post-hatch performance of chicks. A narrow hatch window is needed for commercial poultry industry to acquire a high level of uniformity of chick quality. Hatching synchronization observed...

["Agricultural Science","Animal Behavior","Conservation Biology","Developmental Biology","Zoology"]
doi:10.7717/peerj.4634
69 downloads
191 views

Sclerochronology is presented as an approach to reconstruct, from linear growth records, environmental conditions. This was proposed by analogy with dendrochronology, but shells differ from trees since shells increase in size by terminal, instead of radial, growth....

["Developmental Biology","Ecology","Evolutionary Studies","Mathematical Biology","Environmental Impacts"]
doi:10.7287/peerj.preprints.26827v1

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