120 downloads
580 views

The archaellum, the rotating motility structure of archaea, is best studied in the crenarchaeon Sulfolobus acidocaldarius. To better understand how assembly and rotation of this structure is driven, two ATP-binding proteins, FlaI and FlaH of the motor complex of...

["Biochemistry","Microbiology","Molecular Biology"]
doi:10.7717/peerj.4984
428 downloads
1,345 views

Every cell in an individual has largely the same genomic sequence and yet cells in different tissues can present widely different phenotypes. This variation arises because each cell expresses a specific subset of genomic instructions. Control over which instructions,...

["Biochemistry","Genetics","Molecular Biology","Metabolic Sciences"]
doi:10.7717/peerj.5062
130 downloads
716 views

Thymidylate synthase (TS, E.C. 2.1.1.45) is a crucial enzyme for de novo deoxythymidine monophosphate (dTMP) biosynthesis. The gene for this enzyme is thyA, which encodes the folate-dependent TS that converts deoxyuridine monophosphate group (dUMP) into (dTMP)...

["Aquaculture, Fisheries and Fish Science","Biochemistry","Marine Biology","Microbiology","Drugs and Devices"]
doi:10.7717/peerj.5023
547 downloads
643 views

The existence of eukaryotic ribosomes with distinct ribosomal protein (RP) stoichiometry and regulatory roles in protein synthesis been speculated for over sixty years. Recent advances in mass spectrometry and high throughput analysis have begun to identify and...

["Biochemistry","Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.26991v1
2 citations
157 downloads
963 views

Chemokine (C-C motif) ligand 7 (CCL7), a CC chemokine, is a chemotactic factor and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is widely expressed in multiple cell types and can participate in anti-inflammatory responses...

["Biochemistry","Cell Biology","Molecular Biology","Oncology"]
doi:10.7717/peerj.4928
178 downloads
707 views

We applied multi-omics approaches (transcriptomics, proteomics and metabolomics) to study the effect of iron starvation on the Gram-positive human pathogen Streptococcus pneumoniae to elucidate global changes in the bacterium in a condition similar to what can...

["Biochemistry","Microbiology","Data Science"]
doi:10.7717/peerj.4966
1 citation
322 downloads
1,544 views

Salt bridges form between pairs of ionisable residues in close proximity and are important interactions in proteins. While salt bridges are known to be important both for protein stability, recognition and regulation, we still do not have fully accurate predictive...

["Biochemistry","Computational Biology"]
doi:10.7717/peerj.4967
58 downloads
155 views

Intact biomolecules carry its identity through its atomic constituents and mass, while fragmented biomolecules require reconstruction for their identity to be retrieved. Hence, for profiling biomolecules in mixtures, the goal would be the gentle ionization of biomolecules...

["Biochemistry","Bioengineering","Biophysics","Biotechnology","Cell Biology"]
doi:10.7287/peerj.preprints.26983v1
143 downloads
652 views

L-amino acid oxidases (LAAOs) are ubiquitous enzymes in nature. Bioactivities described for these enzymes include apoptosis induction, edema formation, induction or inhibition of platelet aggregation, as well as antiviral, antiparasite, and antibacterial actions....

["Biochemistry","Biotechnology","Microbiology","Toxicology"]
doi:10.7717/peerj.4924
1 citation
164 downloads
729 views

Background Pyruvate kinase (PK) is responsible for the final reaction in glycolysis. As PK is a glycolytic control point, the analysis of PK posttranslational modifications (PTM) and kinetic changes reveals a key piece of the reorganization of energy metabolism...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.4918
1 citation
195 downloads
878 views

Late embryogenesis abundant (LEA) proteins accumulate in plants during adverse conditions and their main attributed function is to confer tolerance to stress. One of the deleterious effects of the adverse environment is the accumulation of metal ions to levels...

["Biochemistry","Biophysics","Plant Science"]
doi:10.7717/peerj.4930
4 citations
219 downloads
909 views

Tenderness and intramuscular fat content are key attributes for beef sensory qualities. Recently some proteomic analysis revealed several proteins which are considered as good biomarkers of these quality traits. This study focuses on the analysis of 20 of these...

["Agricultural Science","Biochemistry","Food Science and Technology","Genomics"]
doi:10.7717/peerj.4891
164 downloads
702 views

Background The highly valued medicinal tiger milk mushroom (also known as Lignosus rhinocerus) has the ability to cure numerous ailments. Its anticancer activities are well explored, and recently a partially purified cytotoxic protein fraction termed F5 from the...

["Biochemistry","Genetics","Oncology","Translational Medicine","Data Mining and Machine Learning"]
doi:10.7717/peerj.4940
349 downloads
2,032 views

Background Carnivorous plants have been fascinating researchers with their unique characters and bioinspired applications. These include medicinal trait of some carnivorous plants with potentials for pharmaceutical industry. Methods This review will cover recent...

["Biochemistry","Biotechnology","Genomics","Plant Science"]
doi:10.7717/peerj.4914
3 citations
260 downloads
830 views

Conventional aquaculture feed materials available in Australia are expensive, which has prompted the search for alternatives that would be cost-effective and locally available. The present study was undertaken in order to maximize the use of a tuna hydrolysate...

["Aquaculture, Fisheries and Fish Science","Biochemistry","Histology"]
doi:10.7717/peerj.4870

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