1 citation
65 downloads
282 views

Background Respondent fatigue, also known as survey fatigue, is a common problem in the collection of survey data. Factors that are known to influence respondent fatigue include survey length, survey topic, question complexity, and open-ended question type. There...

["Anaesthesiology and Pain Management","Global Health","Statistics","Human\u2013Computer Interaction"]
doi:10.7717/peerj.3785
88 downloads
536 views

Background New-onset atrial fibrillation (AF) is the most common arrhythmia in critically ill patients. Although evidence base and expert consensus opinion for management have been summarised in several international guidelines, no specific considerations for critically...

["Anaesthesiology and Pain Management","Cardiology","Emergency and Critical Care"]
doi:10.7717/peerj.3716
32 downloads
199 views

Background Because etomidate induces prolonged adrenal suppression, even following a single bolus, its use as an infused anesthetic is limited. Our previous study indicated that a single administration of the novel etomidate analog methoxyethyletomidate hydrochloride...

["Animal Behavior","Neuroscience","Veterinary Medicine","Anaesthesiology and Pain Management"]
doi:10.7717/peerj.3693
44 downloads
246 views

Background Hypoxia-inducible factor (HIF)-1 is involved in the regulation of hypoxic preconditioning in cardiomyocytes. Under hypoxic conditions, HIF-1α accumulates and is translocated to the nucleus, where it forms an active complex with HIF-1β and activates transcription...

["Cell Biology","Anaesthesiology and Pain Management","Cardiology"]
doi:10.7717/peerj.3662
93 downloads
950 views

Background Previous studies in human patients suggest depth of sedation may be affected by environmental noise or music; however, related data in domestic animals is limited. The objective of the current study was to investigate the effect of noise and music on...

["Animal Behavior","Veterinary Medicine","Anaesthesiology and Pain Management"]
doi:10.7717/peerj.3659
58 downloads
139 views

Role of glial cells in pain modulation has recently gathered attention. The objective of this study was to determine healthy spinal microglia and astrocyte morphology and disposition in equine spinal cord dorsal horns using Iba-1 and GFAP/Cx-43 immunofluorescence...

["Molecular Biology","Neuroscience","Veterinary Medicine","Anaesthesiology and Pain Management"]
doi:10.7287/peerj.preprints.3066v1
101 downloads
405 views

Background Deliberate hypotension is one way to achieve a bloodless surgical field in endoscopic sinus surgery (ESS). We compared two anaesthesia regimens to induce deliberate hypotension and attempted to determine the most efficient one. Methods Fifty-nine patients...

["Anaesthesiology and Pain Management","Clinical Trials","Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3370
21 downloads
161 views

Background: Chronic diseases have become a global public health issue, and mass media campaigns are often used to encourage and sustain positive behavior change. Our aim was to evaluate the effect of public service advertising on the awareness of Chongqing citizens....

["Anaesthesiology and Pain Management"]
doi:10.7287/peerj.preprints.2985v1
25 downloads
218 views

Background: Respondent fatigue, also known as survey fatigue, is a common problem in the collection of survey data. Factors that are known to influence respondent fatigue include survey length, survey topic, question complexity, and open-ended question type. There...

["Anaesthesiology and Pain Management","Global Health","Statistics","Human-Computer Interaction"]
doi:10.7287/peerj.preprints.2939v1
88 downloads
211 views

Historically, handling insects has usually involved their being killed, but non-lethal approaches are necessary when evaluating the biology of such organisms. Anesthesia has been used as one of these non-lethal approaches. Two common anesthetics used in this way...

["Entomology","Toxicology","Anaesthesiology and Pain Management"]
doi:10.7287/peerj.preprints.2874v1
1 citation
309 downloads
1,008 views

Background The ergogenic effects of analgesic substances suggest that pain perception is an important regulator of work-rate during fatiguing exercise. Recent research has shown that endogenous inhibitory responses, which act to attenuate nociceptive input and...

["Neuroscience","Anaesthesiology and Pain Management","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.3028
321 downloads
1,816 views

Background Illusions that alter perception of the body provide novel opportunities to target brain-based contributions to problems such as persistent pain. One example of this, mirror therapy, uses vision to augment perceived movement of a painful limb to treat...

["Neuroscience","Anaesthesiology and Pain Management","Drugs and Devices","Human-Computer Interaction"]
doi:10.7717/peerj.3023
41 downloads
258 views

Background. Osteoarthritis is the leading cause of chronic joint pain, causing important productivity and economic losses. It is believed that peripheral and centralized sensitization play a role in the creation and maintenance of a chronic painful state. Different...

["Anaesthesiology and Pain Management","Pharmacology","Rheumatology","Translational Medicine"]
doi:10.7287/peerj.preprints.2704v1
115 downloads
572 views

Background There is a dearth of drugs to manage a dose-limiting painful peripheral neuropathy induced by paclitaxel in some patients during the treatment of cancer. Gamma-aminobutyric acid transporter-1 (GAT-1) whose expression is increased in the brain and spinal...

["Animal Behavior","Neuroscience","Anaesthesiology and Pain Management","Pharmacology"]
doi:10.7717/peerj.2798
2 citations
158 downloads
506 views

Paclitaxel, a chemotherapeutic agent, causes neuropathic pain whose supraspinal pathophysiology is not fully understood. Dysregulation of sodium channel expression, studied mainly in the periphery and spinal cord level, contributes to the pathogenesis of neuropathic...

["Molecular Biology","Neuroscience","Anaesthesiology and Pain Management","Pharmacology"]
doi:10.7717/peerj.2702

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