90 downloads
492 views

Background Kawasaki disease (KD) is an immune-mediated systemic vasculitis, and infection plays an important role in the pathophysiology of KD. The susceptibility to infectious disease in patients with KD remains largely unclear. This study aimed to investigate...

["Allergy and Clinical Immunology","Cardiology","Immunology","Infectious Diseases","Pediatrics"]
doi:10.7717/peerj.4539
117 downloads
570 views

This study assessed in detail the influence of four different human proteins on the activation of CD4+ and CD8+ T lymphocytes and on the formation of regulatory T cells. Human whole-blood samples were incubated with four different human proteins. The effects of...

["Allergy and Clinical Immunology","Immunology","Internal Medicine","Pathology","Pediatrics"]
doi:10.7717/peerj.4462
317 downloads
666 views

Background Beaches are recreational spots for people. However, beach sand contains harmful microbes that affect human health, and there are no established methods for either sampling and identifying beach-borne pathogens or managing the quality of beach sand. Method...

["Biotechnology","Marine Biology","Allergy and Clinical Immunology","Pathology","Public Health"]
doi:10.7717/peerj.4245
61 downloads
147 views

Background. Severe equine asthma is a chronic inflammatory disease of the lung in horses similar to low-Th2 late-onset asthma in humans. The disease in horses has complex inheritance including both dominant and recessive patterns that are ill defined. This study...

["Genetics","Veterinary Medicine","Allergy and Clinical Immunology","Respiratory Medicine"]
doi:10.7287/peerj.preprints.3491v1
153 downloads
1,239 views

Energy buffering systems are key for homeostasis during variations in energy supply. Spiders are the most important predators for insects and therefore key in terrestrial ecosystems. From biomedical interest, spiders are important for their venoms and as a source...

["Biochemistry","Biophysics","Zoology","Allergy and Clinical Immunology"]
doi:10.7717/peerj.3787
4 citations
149 downloads
866 views

Background Oxytetracycline (OTC), which is largely employed in zootechnical and veterinary practices to ensure wellness of farmed animals, is partially absorbed within the gastrointestinal tract depositing in several tissues. Therefore, the potential OTC toxicity...

["Cell Biology","Allergy and Clinical Immunology","Drugs and Devices","Immunology","Pharmacology"]
doi:10.7717/peerj.3236
1 citation
192 downloads
853 views

This study investigated the mechanism of protein disulfide-isomerase A3 (PDIA3)-induced visceral hypersensitivity in irritable bowel syndrome (IBS). Rats were treated with saline (control), acetic acid and restraint stress (IBS model), empty vector (RNAi control)...

["Allergy and Clinical Immunology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.2644
3 citations
386 downloads
796 views

Introduction Rituximab (RTX) is a B cell-depleting agent approved for the treatment of granulomatosis with polyangiitis (GPA). RTX reduces antibody producing precursor plasma cells and inhibits B and T cells interaction. Infections related to T cell immunodeficiency...

["Allergy and Clinical Immunology","Internal Medicine","Rheumatology"]
doi:10.7717/peerj.2487
496 downloads
361 views

Different types of stem cells are targeted by a number of cytokines that alter proliferation, differentiation, or other properties of stem cells. Stem cells are known to express various cytokine genes. As IL-12, IL-14, G-CSF, and GM-CSF expression is lost after...

["Allergy and Clinical Immunology","Immunology"]
doi:10.7287/peerj.preprints.2347v1
2 citations
236 downloads
906 views

Background. CD8+ T lymphocytes are known to play a critical role in the pathogenesis of chronic obstructive pulmonary disease (COPD). However, systematic analyses of CD8+ T cell (Cytotoxic T cells, Tc) subsets in COPD patients have yet to be well conducted. Methods....

["Allergy and Clinical Immunology","Immunology","Respiratory Medicine"]
doi:10.7717/peerj.2301
434 downloads
379 views

A 6-year-old female Shetland Sheepdog with a history of cardiorespiratory compromise during general anaesthesia was referred for ovariohysterectomy surgery. Clinical examination was unremarkable at presentation and physiologic parameters under general anaesthesia...

["Allergy and Clinical Immunology","Anesthesiology and Pain Management","Emergency and Critical Care","Pharmacology","Veterinary Medicine"]
doi:10.7287/peerj.preprints.2275v1
5 citations
562 downloads
1,804 views

Background. Resveratrol is a natural polyphenol that exhibits anti-inflammatory effects. The aim of this study was to investigate the effects of resveratrol treatment on epithelium-derived cytokines and epithelial apoptosis in a murine model of atopic dermatitis-like...

["Allergy and Clinical Immunology","Dermatology","Immunology"]
doi:10.7717/peerj.1889
308 downloads
1,192 views

Background. Previous studies have shown that psychological stress is linked to asthma prevalence. Parental psychological stress may potentially influence inflammatory responses in their allergic children. The purpose of this study is to clarify the association...

["Allergy and Clinical Immunology","Epidemiology","Nursing","Pediatrics","Psychiatry and Psychology"]
doi:10.7717/peerj.1585
2 citations
232 downloads
1,305 views

Objective. Chronic nasal carriage of Staphylococcus aureus (SA) increases the risk of relapse while Rituximab (RTX) is an effective agent for inducing and maintaining remission in patients with Granulomatosis with polyangiitis (GPA). We investigated whether B cell...

["Allergy and Clinical Immunology","Immunology","Infectious Diseases","Internal Medicine","Rheumatology"]
doi:10.7717/peerj.1051
48 downloads
376 views

Objective: Chronic nasal carriage of Staphylococcus aureus (SA) increases the risk of relapse while Rituximab (RTX) is an effective agent for inducing and maintaining remission in patients with Granulomatosis with polyangiitis (GPA). We investigated whether B cell...

["Allergy and Clinical Immunology","Immunology","Infectious Diseases","Internal Medicine","Rheumatology"]
doi:10.7287/peerj.preprints.972v1

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