[Experimental] List of manuscripts available for review volunteers
2 manuscripts available for review volunteers
November 9, 2017
Anogenital warts are caused by human papillomavirus (HPV). HPV genotype 6 and 11 are most often associated with anogenital warts. The diversity of HPV genotypes found in Thai patients with genital warts is not well-characterized. The objective of this study was to investigate HPV-associated anogenital warts in the Thai population and whether genotypes found are represented in the vaccine. A total of 206 anogenital swab samples were analyzed for HPV DNA by PCR and sequencing. HPV positive was identified in 88.3% (182/206) of the samples. The majority of HPV (75.2%) were low-risk genotypes HPV6 and HPV11. Thus, HPV6 and HPV11 were most common infection in genital wart. We conclude that the quadrivalent vaccine could potentially prevent 84.5% of the genital warts found in the Thai population.
October 28, 2017
Background : Although, most of the research focus on the effect of birth methods on postpartum hemorrhage (PPH), there is, however, a lack of studies that examine whether the association between PPH and birth methods is different between nulliparous and multiparous women. We aims to compare the effects of birth methods on PPH between nulliparous and multiparous women. Methods: The data on 151,333 eligible women, who gave birth between January 2014 and May 2016, was obtained from the electronic health records in Shanxi province, China. The ordered logistic regression model was used to examine the association of birth methods and varying degrees of PPH between nulliparous and multiparous women. Results: In comparison with the odds for SVB, the odds of increased PPH for CS in multiparous women (aOR: 4.32; 95% CI: 3.03-6.14) was more than twice that in the nulliparous women (aOR: 2.04; 95% CI: 1.40-2.97). However, the PPH risk for episiotomy between multiparous (aOR: 1.24; 95% CI: 0.96-1.62) and nulliparous women (aOR: 1.55; 95% CI: 0.92-2.60) were nearly the same. The PPH risk of forceps-assisted birth was much higher in multiparous women (aOR: 9.32; 95% CI: 3.66-23.71) than in nulliparous women (aOR: 1.70; 95% CI: 0.91-3.18). Meanwhile, that for vacuum-assisted birth in multiparous women (aOR: 2.41; 95% CI: 0.36-16.29) was more than twice the PPH risk in the nulliparous women (aOR: 1.05; 95% CI: 0.40-2.73). However, the difference was insignificant. Uterine inertia was more prone to cause PPH in the multiparous women (aOR: 5.54; 95% CI: 1.76-17.50) than in the nulliparous women (aOR: 3.03; 95% CI: 1.48-6.21). In contrast to uterine inertia, vertex malposition presented a decreased effect to the development of PPH in the multiparous (aOR: 1.93; 95% CI: 1.25-3.00) and nulliparous women (aOR: 0.87; 95% CI: 0.63-1.22). Conclusion: The associations between birth methods and PPH are different between nulliparous and multiparous women. Therefore, the choice of birth methods should be tailored for nulliparous and multiparous women at labor to lower the severity of postpartum hemorrhage.


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