Intramedullary nailing versus external fixation for pediatric tibial fractures: a systematic review and meta-analysis of functional outcomes and complications


Abstract

Background: In pediatric tibial fracture treatment, surgical methods such as Elastic Stable Intramedullary Nailing (ESIN) and External Fixation (EF) are typically selected based on injury mechanism. A systematic comparison of their clinical outcomes is warranted. This study evaluates differences in postoperative efficacy and complications between ESIN and EF, aiming to improve prognostic assessment and optimize clinical management.
Methods: A systematic search of online databases identified studies comparing ESIN and EF in pediatric tibial fractures with reported clinical outcomes. Meta-analysis was conducted on bone growth-related indicators (healing time, malunion, delayed union, reoperation rate) and other complications (pin tract infection, skin lesions, compartment syndrome).
Results: Eight studies involving 364 patients (221 ESIN, 143 EF) were included. ESIN showed significantly shorter healing time (MD: - 5.75 days; 95% CI: - 8.76 to - 2.75; P = 0.0002), lower reoperation rate (OR: 0.27; 95% CI: 0.13–0.56; P = 0.0003), and reduced malunion incidence (OR: 0.26; 95% CI: 0.11–0.63; P = 0.003). Delayed union was more frequent in the EF group but not statistically significant (OR: 0.80; 95% CI: 0.26–2.44; P = 0.70). Overall complication rate was lower with ESIN (OR: 0.39; 95% CI: 0.21–0.71; P = 0.002).
Conclusion: Both ESIN and EF are effective for pediatric tibial fractures, each with specific indications. ESIN demonstrates advantages in bone healing and complication rates, while EF remains essential in complex or open fractures.
Ask to review this manuscript

Notes for potential reviewers

  • Volunteering is not a guarantee that you will be asked to review. There are many reasons: reviewers must be qualified, there should be no conflicts of interest, a minimum of two reviewers have already accepted an invitation, etc.
  • This is NOT OPEN peer review. The review is single-blind, and all recommendations are sent privately to the Academic Editor handling the manuscript. All reviews are published and reviewers can choose to sign their reviews.
  • What happens after volunteering? It may be a few days before you receive an invitation to review with further instructions. You will need to accept the invitation to then become an official referee for the manuscript. If you do not receive an invitation it is for one of many possible reasons as noted above.

  • PeerJ does not judge submissions based on subjective measures such as novelty, impact or degree of advance. Effectively, reviewers are asked to comment on whether or not the submission is scientifically and technically sound and therefore deserves to join the scientific literature. Our Peer Review criteria can be found on the "Editorial Criteria" page - reviewers are specifically asked to comment on 3 broad areas: "Basic Reporting", "Experimental Design" and "Validity of the Findings".
  • Reviewers are expected to comment in a timely, professional, and constructive manner.
  • Until the article is published, reviewers must regard all information relating to the submission as strictly confidential.
  • When submitting a review, reviewers are given the option to "sign" their review (i.e. to associate their name with their comments). Otherwise, all review comments remain anonymous.
  • All reviews of published articles are published. This includes manuscript files, peer review comments, author rebuttals and revised materials.
  • Each time a decision is made by the Academic Editor, each reviewer will receive a copy of the Decision Letter (which will include the comments of all reviewers).

If you have any questions about submitting your review, please email us at [email protected].