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I comment that authors have done remarkable job. This is exciting story, which shows rubromycin-based lead compounds for HIV-1 reverse transcriptase (HIV1-RT) inhibition. Herein Authors have carried out molecular docking (particularly MM/PBSA simulations) studies and illustrated that γ -rubromycin-based ligands are able to bind to HIV1-RT at the NNRTI-binding site. Authors unraveled that these li...

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