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Supplemental Information

Supporting Figures

Single pdf file containing Supporting Figures S1-S9.

DOI: 10.7287/peerj.preprints.74v1/supp-1

Additional Information

Competing Interests

No competing interests.

Author Contributions

Eleisha L. Jackson conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper.

Noah Ollikainen conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, wrote the paper.

Arthur W. Covert III conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, wrote the paper.

Tanja Kortemme conceived and designed the experiments, wrote the paper.

Claus O. Wilke conceived and designed the experiments, wrote the paper.

Grant Disclosures

The following grant information was disclosed by the authors:

NIH grant R01 GM088344

DTRA grant HDTRA1-12-C-0007

NSF grant CAREER MCB-0744541

NSF grant DBI-1262182

Funding

This work was supported in part by NIH grant R01 GM088344 and by DTRA grant HDTRA1-12-C-0007 to C.O.W. and by NSF grants CAREER MCB-0744541 and DBI-1262182 to T.K. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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