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Additional Information

Competing Interests

The authors declare they have no competing interests.

Author Contributions

David S Smith conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Xia Li analyzed the data, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Lori R Arlinghaus performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, reviewed drafts of the paper, collection of in vivo data.

Thomas E Yankeelov contributed reagents/materials/analysis tools, reviewed drafts of the paper, iRB approval; collection of in vivo data.

E. Brian Welch performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

1. Vanderbilt Ingram Cancer Center Institutional Review Board

2. Protocol BRE 0588: MRI Evaluation Of Breast Tumor Growth And Treatment Response

Data Deposition

The following information was supplied regarding the deposition of related data:

http://github.com/davidssmith/DCEMRI.jl

Funding

This project was funded by the National Cancer Institute of the National Institutes of Health, under Award Numbers K25CA176219, U01CA142565, R01CA129961, R25CA092043. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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