Multidimensional scaling of gene expression
Multidimensional scaling of overall gene expression (A) identifies distinct clusters of male and female nematodes. Using the same technique on the subset of genes identified in generalized linear models for genes putativelydiffering for both nematode population (B) and experimental host species (C) does not generate robust clustering.
Relationships of genotypic differentiation measures
Panel A depicts the high correlation of the contribution to the discriminant
function between populations and fixation index Fst. Panel
B shows the density distributions of different measures of
differentiation separately for SNPs with different effect on the
protein sequence. Highly differentiating SNPs are enriched for
synonymous and non-coding polymorphism over of non-synonymous
differences. In Panel C dn/ds is plotted against the maximal per gene differentiation (over loci), the green and blue line s give thresholds for “high differentiation” (maximal contribution to discriminant function > 0.8x10-5) and “positive selection” (dn/ds > 0.5), respectively.