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Additional Information

Competing Interests

There are no competing interests.

Author Contributions

Jonathan M Peterson conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Ryan Mart performed the experiments, reviewed drafts of the paper.

Cherie E Bond performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The diaphragm muscles were kindly provided by the lab of Stephen E Alway. All animal procedures were conducted in accordance with institutional guidelines, and ethical approval was obtained from the Animal Care and Use Committee at West Virginia University (ACUC# 07-0302).

Grant Disclosures

The following grant information was disclosed by the authors:

East Tennessee State University Research Development Committee Major Grants Program (E83044)

Funding

This work was funded all by a grant from the East Tennessee State University Research Development Committee Major Grants Program (E83044). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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