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Additional Information

Competing Interests

The authors declare they have no competing interests.

Author Contributions

Giovanni Messina conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, reviewed drafts of the paper.

Sergio Chieffi conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Marcellino Monda conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The ethics committee of the Second University approval: no.12.1.61.64.72.

Funding

Funding was received from the Fund of Ateneo no.12MM. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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