Growth control of worms treated with the substances
The worms were treated with the highest used concentrations of the extracts and fractions. A reduced body length would point to toxic effects to the worms or antimicrobial properties against the food source of the worms (E. coli). All concentrations were deemed suitable
Raw data of A beta plaques
Single values (mean plaque number of 20-25 worms) of up to 4 independently performed experiments. Results: means, SEM, statistics
Raw data of paralysis assay
First sheet: Single values (median values obtained from Kaplan-Meier analysis) of 4 independently performed experiments. Results: means, SEM, statistics
Second sheet: % of worms (test strain CL4176 expressing A beta) not paralysed for every time point. Data used for creating the graphs
Third sheet: % of worms (control strain CL802 not expressing A beta) not paralysed for every time point. Worms were treated with the highest concentration of the respective extract/ fraction. As worms were not paralysing, the delayed paralysis of CL4176 can be attributed to A beta-counteracting effects of the test substances.