Myelin can't change the basic mechanisms of axonal conduction
Department of Pharmacy, University of Genoa, Genoa, Italy
- Published
- Accepted
- Subject Areas
- Biochemistry, Neuroscience, Neurology
- Keywords
- Nerve conduction, Myelin, ATP, Neuroenergetic
- Copyright
- © 2017 Morelli et al.
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
- Cite this article
- 2017. Myelin can't change the basic mechanisms of axonal conduction. PeerJ Preprints 5:e3409v1 https://doi.org/10.7287/peerj.preprints.3409v1
Abstract
We propose a new hypothesis about the physical-chemical mechanisms of nerve conduction in myelinated nerves, tending to bridge the theoretical gap existing to date between the basic neuronal activity and its adaptation to myelination. All the considerations imply a simplification of the underlying theories, identifying a precise role for myelin. The ATP-supplying energetic role for myelin allows to overcome the theories that have not yet found a physical-chemical solid confirmation. A radical simplification of nerve conduction mechanism is envisaged: it can be supposed that this mechanism remains unaltered in the passage from the unmyelinated to the myelinated conditions.
Author Comment
This is a preprint submission to PeerJ Preprints.