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Effect of an oral dietary supplementation by a formulation based on silibinin-phosphatidylcholine complex in cats with liver diseases

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38 days ago
Effect of an oral dietary supplementation by a formulation based on silibinin-phosphatidylcholine complex in cats… https://t.co/UFRdV7T7YR
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Supplemental Information

Additional Information

Competing Interests

LeG and MB are employees of Candioli Farmaceutici S.p.A. ST is employee of Indena S.p.A. LuG is a consultant of Indena S.p.A.

Author Contributions

Elena Biasibetti conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Tiziana Cocca conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, prepared figures and/or tables, reviewed drafts of the paper.

Maria Teresa Capucchio performed the experiments, contributed reagents/materials/analysis tools, prepared figures and/or tables, reviewed drafts of the paper.

Stefano Togni conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Luca Giacomelli analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Leonardo Giraudo performed the experiments, contributed reagents/materials/analysis tools, prepared figures and/or tables, reviewed drafts of the paper.

Mauro Bigliati performed the experiments, contributed reagents/materials/analysis tools, prepared figures and/or tables, reviewed drafts of the paper.

Marco Barbara conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The proof of approval is missing because silibinin-phosphatidylcholine complex is classified as a feed material (and not veterinary drug) according to Regulation (EC) No 7672009 and the approval is not necessary or raccomandated. Owners gave informed written consent for their cats to participate in the study and were free to withdraw at any time without prior notice. The clinical investigations and treatment are appropriate and necessary for animal with this pathology.

Data Deposition

The following information was supplied regarding data availability:

Raw data is uploaded as a supplemental file.

Funding

The authors received no funding for this work.


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