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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Francesco Guarino conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, performed the computation work, reviewed drafts of the paper.

Mario Alessandro Russo performed the experiments, analyzed the data, wrote the paper, reviewed drafts of the paper.

Monica Franzese conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, performed the computation work, reviewed drafts of the paper.

Dario Righelli performed the experiments, performed the computation work, reviewed drafts of the paper.

Giovanni Improta contributed reagents/materials/analysis tools.

Claudia Angelini conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Maria Triassi contributed reagents/materials/analysis tools.

Data Deposition

The following information was supplied regarding data availability:

The research in this article did not generate any data or code.

Funding

This work was supported by Department of Health, University of Naples. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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