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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Alessandro Zandonà conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, performed the computation work, reviewed drafts of the paper.

Matilde Francescon conceived and designed the experiments, performed the experiments, analyzed the data, performed the computation work.

Maya Bronfeld wrote the paper, reviewed drafts of the paper.

Andrea Calvo reviewed drafts of the paper.

Adriano Chiò wrote the paper, reviewed drafts of the paper.

Barbara Di Camillo conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, reviewed drafts of the paper.

Data Deposition

The following information was supplied regarding data availability:

Further analyses have still to be performed on data

Funding

This work was funded by the bilateral Italian-Israel project CompALS (Computational analysis of the clinical manifestations and predictive modelling of ALS), supported by the Italian Ministry of Foreign Affairs and International Cooperation and the Ministry of Science, Technology and Space of the State of Israel. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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