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Additional Information

Competing Interests

The authors declare that there are no competing interests.

Author Contributions

Larry Leamy analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Kari Elo conceived and designed the experiments, performed the experiments, reviewed drafts of the paper.

Merlyn K Nielsen conceived and designed the experiments, performed the experiments, reviewed drafts of the paper.

Stephanie Thorn performed the experiments, reviewed drafts of the paper.

William Valdar analyzed the data, reviewed drafts of the paper.

Daniel Pomp conceived and designed the experiments, performed the experiments, wrote the paper, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

University of Nebraska-Lincoln Animal Care and Use Committee. Protocol 2-2-010

Grant Disclosures

The following grant information was disclosed by the authors:

NIH grants GM060029, DK076050 and DK056350.

Funding

We received support from NIH grants GM060029, DK076050 and DK056350. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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