The Ax21 protein influences virulence and biofilm formation in the nosocomial pathogen Stenotrophomonas maltophilia
1
School of Life Sciences, University of Dundee, Dundee, United Kingdom
2
College of Life Science and Technology, Guangxi University, Nanning, China
- Published
- Accepted
- Subject Areas
- Microbiology, Molecular Biology
- Keywords
- virulence, biofilm, antibiotic resistance, stenotrophomonas
- Copyright
- © 2017 An et al.
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
- Cite this article
- 2017. The Ax21 protein influences virulence and biofilm formation in the nosocomial pathogen Stenotrophomonas maltophilia. PeerJ Preprints 5:e2955v1 https://doi.org/10.7287/peerj.preprints.2955v1
Abstract
Stenotrophomonas maltophilia is an antibiotic resistant Gram-negative pathogen, which is associated with hospital-acquired infection. The genome encodes a protein highly related to the Ax21 protein of Xanthomonas oryzae pv. oryzae that is implicated in interactions of this plant pathogen with rice. Here we show that loss by mutation of Ax21 influences a variety of functions in Stenotrophomonas maltophilia, to include virulence, antibiotic resistance and biofilm formation in this nosocomial pathogen.
Author Comment
This is a preprint submission to Peer J Preprints.