Visitors   Views   Downloads

Tissue-specific expression of NANOG gene in human eye

View preprint
23 days ago
Tissue-specific expression of NANOG gene in human eye https://t.co/68N9ETcQXt https://t.co/OBKzx2Y8Qf
NOT PEER-REVIEWED
"PeerJ Preprints" is a venue for early communication or feedback before peer review. Data may be preliminary.

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Yuliya Markitantova conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Yulia Smirnova performed the experiments, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Rina Zinovieva conceived and designed the experiments, analyzed the data, authored or reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Ethics Committee of the Koltzov Institute of Developmental Biology Russian Academy of Science granted Ethical approval to carry out the study within its facilities.

Field Study Permissions

The following information was supplied relating to field study approvals (i.e., approving body and any reference numbers):

Experiments were approved by the Research Center of Obstetrics, Gynecology, and Perinatology, Russian Academy of Medical Sciences; Ethics Committee of the Koltzov Institute of Developmental Biology Russian Academy of Science (Ethical Application Ref: № 22, 15 March 20018)

Data Deposition

The following information was supplied regarding data availability:

In this study we have studied the distribution of NANOG mRNA in the human eye tissues at the early developmental stages. We confirmed our previous PCR results shown in the article "Identification of the OCT4-pg1 retrogene and NANOG gene expression in the human embryonic eye, published in Biology Bulletin 35:108–12, 2008.

Funding

This research was funded by Government program of basic research, number 0108-2019-0005. The research was performed using equipment of the Core Centrum of Institute of Developmental Biology RAS. Authors thank Prof. Sukhikh G.T., PhD, Poltavzeva R.A., from the Research Center of Obstetrics, Gynecology and Perinatology, Russian Academy of Medical Sciences, Moscow, for providing the of post-operating eyes from different stages of human development for the study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


Add your feedback

Before adding feedback, consider if it can be asked as a question instead, and if so then use the Question tab. Pointing out typos is fine, but authors are encouraged to accept only substantially helpful feedback.

Some Markdown syntax is allowed: _italic_ **bold** ^superscript^ ~subscript~ %%blockquote%% [link text](link URL)
 
By posting this you agree to PeerJ's commenting policies