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Cell lineage trees: the central structure plus key dynamics of biological aging and formulating the limiting problem of comprehensive organismal rejuvenation

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published new version (v6) 829 words added as 4. point of macro-argument entitled The most comprehensive medical solution of biological aging(s) needs to use individual cell lineage trees as a central tool for diagnosis and treatment, plus references
RT @attilacsordas: I've been thinking sporadically but intensively on the role cell lineage trees might play in #aging/#longevity intervent…
@LucieLaplane @pradeu @AndreasBikfalvi Lucie, here's the perspective paper behind my question in the context of stem cell niche, see 3. Objections against the centrality of tree dynamics in aging and Tissue microenvironments: stem cell niche
I've been thinking sporadically but intensively on the role cell lineage trees might play in #aging/#longevity interventions in the last 11 years, so I thought I summarise it as a perspective piece & publish as a preprint at @PeerJPreprints
"PeerJ Preprints" is a venue for early communication or feedback before peer review. Data may be preliminary.

Additional Information

Competing Interests

Attila Csordas is the founder of Cell Tree Resources.

Author Contributions

Attila Csordas conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Data Deposition

The following information was supplied regarding data availability:

This is an opinion article.


The author received no funding for this work.

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