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Cell lineage trees: the central structure plus key dynamics of biological aging and formulating the limiting problem of comprehensive organismal rejuvenation

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@heffersbookshop @wtgowers @emblebi Day #3 studying PCM p1004 Bela Bollobas' tautological hint: 'you should choose problems you find it difficult not to think about' to me THE problem couldn't help but think a lot on are cell lineage trees & aging, https://t.co/Z7s4riCWMC discussed it w/Bollobas @ @TrinCollCam :)
32 days ago
Cell lineage trees: the central structure plus key dynamics of biological aging and formulating the limiting problem of comprehensive organismal rejuvenation https://t.co/1etAfdOl3U https://t.co/bB6kqylZwQ
update to my @PeerJPreprints perspective piece on the role cell lineage trees might play in understanding biological #aging and developing a new medical paradigm around comprehensive rejuvenation to at least advance feasible healthy #longevity https://t.co/Z7s4riCWMC
published new version (v6) 829 words added as 4. point of macro-argument entitled The most comprehensive medical solution of biological aging(s) needs to use individual cell lineage trees as a central tool for diagnosis and treatment, plus references https://t.co/Z7s4riCWMC
RT @attilacsordas: I've been thinking sporadically but intensively on the role cell lineage trees might play in #aging/#longevity intervent…
@LucieLaplane @pradeu @AndreasBikfalvi Lucie, here's the perspective paper behind my question in the context of stem cell niche, see 3. Objections against the centrality of tree dynamics in aging and Tissue microenvironments: stem cell niche https://t.co/Z7s4riCWMC
I've been thinking sporadically but intensively on the role cell lineage trees might play in #aging/#longevity interventions in the last 11 years, so I thought I summarise it as a perspective piece & publish as a preprint at @PeerJPreprints https://t.co/Z7s4riCWMC
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Additional Information

Competing Interests

Attila Csordas is the director/founder of AgeCurve Limited, Cambridge, UK.

Author Contributions

Attila Csordas conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Data Deposition

The following information was supplied regarding data availability:

This is an opinion article.

Funding

The author received no funding for this work.


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