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2018 YPIC Challenge: A case study in characterizing an unknown protein sample

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48 days ago
2018 YPIC Challenge: A case study in characterizing an unknown protein sample https://t.co/BBggQOXBhm https://t.co/9pxZ87audj
RT @neXtProt_news: An unexpected comparison of neXtProt with Fifty Shades of Grey in a Young Proteomics Investigator Club (YPIC) @EU_YPIC c…
90 days ago
RT @neXtProt_news: An unexpected comparison of neXtProt with Fifty Shades of Grey in a Young Proteomics Investigator Club (YPIC) @EU_YPIC c…
An unexpected comparison of neXtProt with Fifty Shades of Grey in a Young Proteomics Investigator Club (YPIC) @EU_YPIC challenge report https://t.co/ZkdExqSYwc https://t.co/hCNrbadqg8
RT @bittremieux: Looking for some fresh #proteomics research after last week's #ASMSATL? Check out our analysis of the 2018 YPIC challenge…
123 days ago
2018 YPIC Challenge: A case study in characterizing an unknown protein sample https://t.co/Rrlzrv41Q4 https://t.co/aABv6BLfo0
123 days ago
RT @bittremieux: Looking for some fresh #proteomics research after last week's #ASMSATL? Check out our analysis of the 2018 YPIC challenge…
RT @bittremieux: Looking for some fresh #proteomics research after last week's #ASMSATL? Check out our analysis of the 2018 YPIC challenge…
123 days ago
Looking for some fresh #proteomics research after last week's #ASMSATL? Check out our analysis of the 2018 YPIC challenge to characterize an unknown protein sample: https://t.co/1GajGqbNCH With @lkpino and Andy Lin. Big thanks to @EU_YPIC for organizing an exciting challenge.
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Supplemental Information

Simulated peptide length for alternative proteases

Length of simulated peptides for various corpuses using alternative proteases including chymotrypsin, Glu-C, Lys-C, Arg-C, Asp-N, pepsin, and a combined digestion with trypsin. NeXtProt is a database of human proteins, whereas Cryptonomicon and 50 Shades of Grey are two English fiction novels.

DOI: 10.7287/peerj.preprints.27802v2/supp-1

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Lindsay Pino conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Andy Lin conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Wout Bittremieux conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Data Deposition

The following information was supplied regarding data availability:

The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with the dataset identifier PXD014003.

Funding

W.B. is a postdoctoral researcher of the Research Foundation – Flanders (FWO). W.B. was supported by a postdoctoral fellowship of the Belgian American Educational Foundation (BAEF). L.K.P. was supported by NIH F31 AG055257. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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