Visitors   Views   Downloads

Brasilia Parkinson Cohort: assessing clinical, neuropsychological and imaging predictors of cognitive decline in Parkinson's disease

View preprint
Brasilia Parkinson Cohort study protocol https://t.co/kSzjF9tq7k via @PeerJPreprints
Coorte Brasília Parkinson. Recrutamento de pacientes com doença de Parkinson para contribuição com o estudo. É realizado na UnB, em parceria com diversas instituições, e visa associar sintomas não motores com medidas estruturais do cérebro. https://t.co/BGmCQ6mt7Q https://t.co/DyoTTmneCs
RT @pedrorpbrandao: Brasilia Parkinson Cohort study protocol https://t.co/v8R6ybCCXM #parkinson #neuroscience #cognition #cognitivedisorder…
Coorte Brasília Parkinson #parkinson #cognition #nonmotorsymptoms #mildcognitiveimpairment https://t.co/dAprRAs44M estudo clínico observacional realizado em Brasília, em busca de biomarcadores de neuroimagem para subtipos da doença de Parkinson
RT @pedrorpbrandao: Brasilia Parkinson Cohort study protocol https://t.co/v8R6ybCCXM #parkinson #neuroscience #cognition #cognitivedisorder…
NOT PEER-REVIEWED
"PeerJ Preprints" is a venue for early communication or feedback before peer review. Data may be preliminary.

Supplemental Information

Figure 1 – Brasilia Parkinson Cohort study design

The figure describes the enrollment process, along with outcome measures, clinical data, neuroimaging and neuropsychological assessments. MRI= Magnetic resonance imaging; CANTAB = Cambridge Automated Neuropsychological Assessment Battery; MoCA= Montreal Cognitive Assessment; PD-CRS=Parkinson’s disease- Cognitive Rating Scale; TMT-A and -B: Trail Making Test Parts A and B; SDMT=Symbol Digit Modalities Test; WAIS-III=Wechsler’s Adult Intelligence Scale 3rdedition; NMSS=Non-motor symptoms scale; BDI= Beck Depression inventory; BSI= Beck Suicide Ideation Scale; HADS= Hospital Anxiety and Depression Scale; PDSS-BR=Parkinson’s disease Sleep Scale, Brazilian version; RBDSQ= Rapid eye movement sleep Behavior Disorder Screening Questionnaire; SAS= Starkstein Apathy Scale; QUIP-CS= Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s disease- Current Short; QUIP-RS= Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s disease- Rating Scale; PD-CFRS= Parkinson’s disease-Cognitive Functional Rating Scale; MDS-UPDRS=International Parkinson and Movement Disorders-Unified Parkinson’s disease Rating Scale; DTI=Diffusion tensor imaging; TFE=turbo field echo; FLAIR=Fluid attenuated inversion recovery; PDQ-8=Parkinson’s disease Questionnaire – Short version (8-item);

DOI: 10.7287/peerj.preprints.27639v1/supp-1

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Pedro Renato de Paula Brandão conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Fernando Bisinoto Maluf conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Talyta Grippe conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Ingrid Faber performed the experiments, analyzed the data, authored or reviewed drafts of the paper, approved the final draft.

Danilo Assis Pereira conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Nasser Allam analyzed the data, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Francisco E.C. Cardoso conceived and designed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Carlos Tomaz analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Maria Clotilde H Tavares conceived and designed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Ethics Committee from Brasilia University Center (UniCEUB)

Data Deposition

The following information was supplied regarding data availability:

When data is fully collected, raw data will be provided in OASIS neuroimaging repository.

Funding

The study is partially supported by a grant from FAP-DF [grant number 193001612/2016]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


Add your feedback

Before adding feedback, consider if it can be asked as a question instead, and if so then use the Question tab. Pointing out typos is fine, but authors are encouraged to accept only substantially helpful feedback.

Some Markdown syntax is allowed: _italic_ **bold** ^superscript^ ~subscript~ %%blockquote%% [link text](link URL)
 
By posting this you agree to PeerJ's commenting policies