Differentiation potential to neural-like cells in human adrenocortical carcinoma SW-13 cells
- Published
- Accepted
- Subject Areas
- Cell Biology, Neuroscience
- Keywords
- SW-13, Adrenocortical carcinoma
- Copyright
- © 2019 Shimada et al.
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
- Cite this article
- 2019. Differentiation potential to neural-like cells in human adrenocortical carcinoma SW-13 cells. PeerJ Preprints 7:e27620v1 https://doi.org/10.7287/peerj.preprints.27620v1
Abstract
Various cancer cells are known to show neural differentiation. Adrenocortical carcinoma (ACC) is a rare and frequently aggressive tumor originating in the cortex of the adrenal gland. Early diagnosis of ACC is challenging due to a lot of unknown aspects such as cell characteristics in a rare cancer. In the present study, morphological features were examined in the adrenal cortex carcinoma cells SW-13 as an initial candidate, which were exposed to neural differentiation condition. SW-13 cells treated with the neural induction supplement showed neural-like differentiation with elongated filaments. It was suggested that SW-13 cells had neural differentiation potential and could be a research tool to elucidate the cell characteristics in future ACC studies.
Author Comment
This is a preprint submission to PeerJ Preprints.