Coleoptera genome and transcriptome sequences reveal numerous differences in neuropeptide signaling between species
- Published
- Accepted
- Subject Areas
- Bioinformatics, Entomology, Genomics, Neuroscience, Zoology
- Keywords
- Neuropeptide, genome, transcriptome, beetle, neuropeptide F, gene duplication, gene loss, CCHamide
- Copyright
- © 2019 Veenstra
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
- Cite this article
- 2019. Coleoptera genome and transcriptome sequences reveal numerous differences in neuropeptide signaling between species. PeerJ Preprints 7:e27561v1 https://doi.org/10.7287/peerj.preprints.27561v1
Abstract
Background. Insect neuropeptides are interesting for the potential their receptors hold as plausible targets for a novel generation of pesticides. Neuropeptide genes have been identified in a number of different species belonging to a variety of insects. Results suggest significant neuropeptide variation between different orders, but much less is known of neuropeptidome variability within an insect order. I therefore compared the neuropeptidomes of a number of Coleoptera. Methodology. Publicly available genome sequences, transcriptomes and the original sequence data in the form of short sequence read archives (SRAs) were analyzed for the presence or absence of genes coding neuropeptides as well as some neuropeptide receptors in seventeen beetle species. Results. Significant differences exist between the Coleoptera analyzed here, while many neuropeptides that were previously characterized from Tribolium castaneum appear very similar in all species, some are not and others are lacking in one or more species. On the other hand, leucokinin, which was presumed to be universally absent from Coleoptera, is still present in non-Polyphaga beetles. Conclusion. The variability in neuropeptidome composition between insect species from from the same insect order may be as large as the one that exists between species from different orders.
Author Comment
This is a submission to PeerJ for review.