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Supplemental Information

Supplementary Table 1

Flygut-seq EE peptide receptor expression: Expression of receptors for enteroendocrine cell-produced peptides in various regions and cell-types of the adult Drosophila midgut. The midgut is divided into five distinct domains (R1-R5) according to Buchon et al 2013. It is comprised of five different cells: visceral muscles (VM), intestinal stem cells (ISC), enteroblasts (EB), enterocytes (EC) and enteroendocrine (EE) cells. The expression of each receptor is color-coded: the tissue with lowest expression is in yellow, medium expression in orange and highest expression in red. The expression of allatostatin A receptor 1 could not be detected. Data based on Flygut-seq [749] .

DOI: 10.7287/peerj.preprints.27515v2/supp-1

Microsoft Word - Suppl. File Appendix 1. R1.docx Supplementary Materials file Appendix 1

Microsoft Word - Suppl. File Appendix 1. R1.docx Brief overview of Drosophila neuropeptides and peptide hormones (Appendix to section 5)

DOI: 10.7287/peerj.preprints.27515v2/supp-2

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Dick R Nässel prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Meet Zandawala prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Data Deposition

The following information was supplied regarding data availability:

This is a review article and does not have any raw data.


The research in our laboratory is funded by the Swedish Research Council (Vetenskapsrådet; 2015-04626), and the European Commission Horizon 2020 (Research and Innovation Grant 634361), both to D.R.N. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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