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Supplemental Information

Additional Information

Competing Interests

Xiangjie Kong is an Academic Editor for PeerJ.

Author Contributions

Xiangjie Kong conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, performed the computation work, authored or reviewed drafts of the paper, approved the final draft.

Lei Liu conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, performed the computation work, authored or reviewed drafts of the paper, approved the final draft.

Shuo Yu performed the experiments, analyzed the data, authored or reviewed drafts of the paper, approved the final draft.

Andong Yang analyzed the data, authored or reviewed drafts of the paper, approved the final draft.

Xiaomei Bai conceived and designed the experiments, analyzed the data, authored or reviewed drafts of the paper, approved the final draft.

Bo Xu conceived and designed the experiments, analyzed the data, authored or reviewed drafts of the paper, approved the final draft.

Data Deposition

The following information was supplied regarding data availability:

The raw code are provided in supplementary file 1.

Funding

This work was partially supported by the Fund for Promoting the Reform of Higher Education by Using Big Data Technology, Energizing Teachers and Students to Explore the Future (2017A01002), the Fundamental Research Funds for the Central Universities (DUT18JC09), Liaoning Provincial Key R\&D Guidance Project (2018104021) and Liaoning Provincial Natural Fund Guidance Plan (20180550011). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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