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Towards predictive biophysical and mechanistic models for disease-causing protein variants

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RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
18 days ago
Towards predictive biophysical and mechanistic models for disease-causing protein variants https://t.co/0eisHBtVAY
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
19 days ago
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
19 days ago
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
19 days ago
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
RT @LindorffLarsen: Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Peter…
Pleased to share our most recent #preprint written together with @amelie_rocks, @dougfowler42 and Rasmus Hartmann-Petersen. This manuscript is a review on biophysical and mechanistic models for disease-causing protein variants. Comments are very welcome https://t.co/U5FrdJN0DG
@LindorffLarsen @glukozica @dougfowler42 @biorxivpreprint Here it is: https://t.co/w2oDyC9gW8 - please read, we’d love feedback! And thanks to @LindorffLarsen for finding it a preprint home!
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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Amelie Stein conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Douglas M Fowler conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Rasmus Hartmann-Petersen conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Kresten Lindorff-Larsen conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Data Deposition

The following information was supplied regarding data availability:

This is a review manuscript.

Funding

Our work in this area has been supported by grants from the Lundbeck Foundation (A.S., R.H.-P. and K.L.-L.), The Danish Cancer Society (R.H.-P.), the Novo Nordisk Foundation (R.H.-P. and K.L.-L.), the Danish Council for Independent Research (Natural Sciences) (to R.H.-P), the National Institute of General Medical Sciences (1R01GM109110 to D.M.F.). D.M.F. is a CIFAR Azrieli Global Scholar. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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