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Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice

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RT @wjinmathbio: My article 'Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice' w…
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My article 'Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice' was one of the top 5 most viewed #DrugsDevices and #MamaticalBiology articles published in @thePeerJ journal in 2018!
RT @ProfMJSimpson: My preprint has been published today in @PeerJPreprints https://t.co/nIxEr7von6 #CellBiology #MathematicalBiology #Drugs…
RT @ProfMJSimpson: My preprint has been published today in @PeerJPreprints https://t.co/nIxEr7von6 #CellBiology #MathematicalBiology #Drugs…
RT @ProfMJSimpson: My preprint has been published today in @PeerJPreprints https://t.co/nIxEr7von6 #CellBiology #MathematicalBiology #Drugs…
RT @ProfMJSimpson: My preprint has been published today in @PeerJPreprints https://t.co/nIxEr7von6 #CellBiology #MathematicalBiology #Drugs…
RT @ProfMJSimpson: My preprint has been published today in @PeerJPreprints https://t.co/nIxEr7von6 #CellBiology #MathematicalBiology #Drugs…
710 days ago
RT @ProfMJSimpson: My preprint has been published today in @PeerJPreprints https://t.co/nIxEr7von6 #CellBiology #MathematicalBiology #Drugs…
My preprint has been published today in @PeerJPreprints https://t.co/nIxEr7von6 #CellBiology #MathematicalBiology #DrugsandDevices
710 days ago
Modelling of the SDF-1/CXCR4 regulated in vivo homing of therapeutic mesenchymal stem/stromal cells in mice https://t.co/1CXcth8MWW
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Supplemental Information

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Wang Jin analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Xiaowen Liang analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft, provided financial support.

Anastasia Brooks performed the experiments, analyzed the data.

Kathryn Futrega performed the experiments, analyzed the data.

Xin Liu performed the experiments, analyzed the data.

Michael R. Doran authored or reviewed drafts of the paper, provided financial support.

Matthew J. Simpson conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Michael S. Roberts conceived and designed the experiments, authored or reviewed drafts of the paper, approved the final draft, provided financial support.

Haolu Wang conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Queensland University of Technology Human Ethics Committee (number: 1000000938)

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Animal Ethics Committee of the University of Queensland (MED/493/15/NHMRC)

Data Deposition

The following information was supplied regarding data availability:

The raw measurements are provided in the supplementary file 2. The raw data shows CXCL12 levels, SDF-1 levels, and MSC doses in the blood and liver, with various liver and MSC conditions.

Funding

This work is supported by grants from the Australian Research Council (DP170100474) and the National Health and Medical Research Council (APP1126091 and APP1141121). Wang Jin is supported by the Queensland University of Technology Vice Chancellor’s Research Fellowship. Michael R. Doran is supported by the National Health and Medical Research Council Career Development Fellowship. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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