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Additional Information

Competing Interests

The authors declare they have no competing interests.

Author Contributions

Jeremy O'Connell conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Mark Tsechansky conceived and designed the experiments, performed the experiments, analyzed the data.

Marguerite West-Driga performed the experiments.

Edward M Marcotte conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Funding

This work was supported by grants from the National Institutes of Health, National Science Foundation, Cancer Prevention Research Institute of Texas, and the Welch (F-1515) Foundation to EMM. MT acknowledges funding and support from Michele Vendruscolo and the University of Cambridge. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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