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Additional Information

Competing Interests

Yosep Ji, Soyoung Park and Wilhelm H Holzapfel have received research grants, via Handong Global University, from CJ CheilJedang Corp., Republic of Korea.

Young Mee Chung, Dahye Jeong and Bongjoon Kim are employed by CJ CheilJedang Corp., Republic of Korea.

Author Contributions

Yosep Ji conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Young Mee Chung performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper.

Soyoung Park performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Dahye Jeong conceived and designed the experiments, contributed reagents/materials/analysis tools.

Bongjoon Kim conceived and designed the experiments, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper.

Wilhelm Heinrich Holzapfel conceived and designed the experiments, contributed reagents/materials/analysis tools, authored or reviewed drafts of the paper, approved the final draft.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The animal study was approved by the Ethical Committee of KPC Ltd. in Korea (P150067) in full compliance with ethical standards as specified by Korean law.

Data Deposition

The following information was supplied regarding data availability:

All relevant data related to this paper are presented in the manuscript.

Funding

This work was supported by the CJ CheilJedang Corporation, Seoul, Republic of Korea. The external funder (CJ CheilJedang Corporation) is represented by three scientist exmployees of CJ Research Center, as co-authors of this paper.


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