Hypothesis of the conjunct expression gene: can random mutation explain the phenotypic variability?
- Published
- Accepted
- Subject Areas
- Animal Behavior, Ecology, Evolutionary Studies, Genetics
- Keywords
- evolution, gametogenesis, transcription, mutation, epigenome, isochores
- Copyright
- © 2018 Zapata Trejo
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
- Cite this article
- 2018. Hypothesis of the conjunct expression gene: can random mutation explain the phenotypic variability? PeerJ Preprints 6:e26862v6 https://doi.org/10.7287/peerj.preprints.26862v6
Abstract
If the environmental conditions can or not influence in the phenotype evolution, is a topic that has been discussed during the last ten years. The epigenome regulates the gene expression of all cells and indicates which specific genes must be transcribed. It is argued that the expression factors that act in specific genes of the somatic cells involved in a behavior also act in the partial transcription of the same genes in the most undifferentiated cells of the germ line. The functional role of the isochores as an epigenetic determinant regulator of the transcription and therefore of gene expression levels is discussed. It is proposed how a probabilistic view of the random mutation can integrate all the evidence pointing to a conjunct phenotype evolution with the environment. This work provides a new point of view on how the environment can influence in adaptation through natural selection considering the theory currently accepted.
Author Comment
Correction in figure 1: meiotic replication.