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Additional Information

Competing Interests

The authors declare that they have no copeting interests

Author Contributions

Ledy H Oliveira conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Larissa Silva Santos conceived and designed the experiments, performed the experiments.

Felipe P G Neves conceived and designed the experiments, performed the experiments, analyzed the data, prepared figures and/or tables, authored or reviewed drafts of the paper, approved the final draft.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The Ethics Committee of the College of Medicine at the Universidade Federal Fluminense approved the protocols for collection and informed consent (CAAE 0037.0.258.000-10).

DNA Deposition

The following information was supplied regarding the deposition of DNA sequences:

These sequences were submitted

to GenBank and recorded under the accession numbers KY348861(88L1WRJ),

KP701189 (88E6RJ), KP70190 (88E7RJ) and KP701191(88LCRRJ).

Funding

This work was supported by the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq No. 303560/2012-6), Pro-Reitoria de Pesquisa e Pós-Graduação da Universidade Federal Fluminense (PROPPi-UFF), and Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ, No. E-26/ 111.255/2014). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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