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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Gerold Baier analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Chris Barnes analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

David Crowe contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Stephen Gilmore contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Uwe Grimm contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Philip Lewis analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, reviewed drafts of the paper.

David Morse contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Clare Sansom wrote the paper, reviewed drafts of the paper.

Robert D C Saunders contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Adrian Shepherd analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Geraint Thomas analyzed the data, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Data Deposition

The following information was supplied regarding data availability:

The research in this article did not generate, collect or analyse any raw data or code.

Funding

This work was supported by the Biotechnology and Biological Sciences Research Council (BBSRC), UK (BB/I014837/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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