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Additional Information

Competing Interests

Dexmedetomidine used at the latter was donated by Zoetis (Zoetis Canada Inc., Kirkland, QC, Canada).

Author Contributions

Marika C Wagner performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Kent G Hecker conceived and designed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Daniel Pang conceived and designed the experiments, analyzed the data, wrote the paper, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

1. University of Calgary Veterinary Sciences Animal Care Committee

2. AC13-0103

Data Deposition

The following information was supplied regarding data availability:

1. Harvard Dataverse

2. doi:10.7910/DVN/GLZVSL

Funding

A summer scholarship stipend provided by Zoetis was awarded to MW. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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