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Additional Information

Competing Interests

Joao B.T. Rocha is an Academic Editor for PeerJ.

Author Contributions

Joao B Rocha conceived and designed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Daiane F. Meinerz performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Josiane Allebrandt performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables.

Emily Pansera Waczuk performed the experiments, contributed reagents/materials/analysis tools.

Felix Soares conceived and designed the experiments.

Waseem Hassan conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Douglas Mariano performed the experiments, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

the guidelines of the committee on care and use of experimental animal resources of the Federal University Of Santa Maria, Brazil (23081.002435/2007-16).

Funding

The financial support of TWAS, CAPES, SAUX, PROAP, CNPq, VITAE, CNPq-INCT for Excitotocity and Neuroprotection is appreciated. FAPERGS-PRONEX and FAPERGS is also acknowledged for financial assistance. Waseem Hassan and JBTR are recipient of CNPq Fellowships. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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