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Additional Information

Competing Interests

Leila Taher is an Academic Editor for PeerJ.

Author Contributions

Tanushree Jaitly conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Niels Schaft reviewed drafts of the paper, other.

Jan Doerrie reviewed drafts of the paper.

Stefanie Gross reviewed drafts of the paper.

Beatrice Schuler-Thurner prepared figures and/or tables, reviewed drafts of the paper.

Olaf Wolkenhauer reviewed drafts of the paper.

Gerold Schuler reviewed drafts of the paper.

Leila Taher contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Shailendra Gupta contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Julio Vera conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Data Deposition

The following information was supplied regarding data availability:

The raw data or code is included in the manuscript.

Funding

The original idea was developed by GS, JV, SKG and LT. RNAseq and WES data analysis was performed by TJ under the supervision of LT. Epitope prediction, docking and molecular simulations were performed by TJ and SKG. All the authors drafted the manuscript. This work was supported by the German Federal Ministry of Education and Research (BMBF) as part of the project e:Bio- MelEVIR [031L0073A to JV]. JV is funded by the German Research Foundation (DFG) through the project the GRK-1660. GS, BST and NS are funded by the DFG through the SFB-643 (Sub-project C1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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