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Additional Information

Competing Interests

The authors have declared no conflict of interest.

Author Contributions

Rui Fang analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Brandie Wagner analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

J. Kirk Harris conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Sophie A Fillon conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

All human species were collected under approval of the Colorado Multiple Institutional Review Board (COMIRB). Written informed consent and HIPAA authorization were obtained from all participants or from parents or legal guardians of participants younger than 18 years. Assent was obtained from all participants under 18 years.

Grant Disclosures

The following grant information was disclosed by the authors:

The authors recognize the support of REDCap for subjects’ database supported by the National Center for Research Resources, the National Center for Advancing Translational Sciences, National Institutes of Health, and Colorado CTSI Grant Number UL1 RR025780. This work was supported by the American Partnership for Eosinophilic Disorders (APFED) Junior Faculty HOPE Research Grant (SF); National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, Colorado CTSI Grant Number KL2 TR000156 (SF) and (RF).

DNA Deposition

The following information was supplied regarding the deposition of DNA sequences:

REDCap

Funding

The authors recognize the support of REDCap for subjects’ database supported by the National Center for Research Resources, the National Center for Advancing Translational Sciences, National Institutes of Health, and Colorado CTSI Grant Number UL1 RR025780. This work was supported by the American Partnership for Eosinophilic Disorders (APFED) Junior Faculty HOPE Research Grant (SF); National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, Colorado CTSI Grant Number KL2 TR000156 (SF) and (RF). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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