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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Bruna Raquel Zancope conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Vanessa B Dainezi performed the experiments, analyzed the data, contributed reagents/materials/analysis tools.

Marinês Nobre-dos-Santos conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Sillas Duarte, Jr performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables.

Vanessa Pardi analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Ramiro M Murata conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Data Deposition

The following information was supplied regarding data availability:

The raw data has been supplied as a Supplemental Dataset.

Funding

Research reported in this publication was supported by: National Center for Complementary and Integrative Health of the National Institutes of Health under award number R00AT006507, CAPES Foundation (Process 2339-15-3) and FAPESP (Process nº 2012/02885-7) from whom the first author received a scholarship. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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