AmrZ is a positive regulator of swimming motility in Pseudomonas stutzeri

Plant Sciences, University of Arizona, Tucson, Arizona, United States
DOI
10.7287/peerj.preprints.2041v1
Subject Areas
Genetics, Microbiology
Keywords
amrZ, Pseudomonas stutzeri, Swimming Motility
Copyright
© 2016 Baltrus et al.
Licence
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
Cite this article
Baltrus DA, Dougherty K, Dias B, Murillo R. 2016. AmrZ is a positive regulator of swimming motility in Pseudomonas stutzeri. PeerJ Preprints 4:e2041v1

Abstract

amrZ, a master regulator protein conserved across Pseudomonads, can be either a positive or negative regulator of swimming motility depending on the species examined. To better understand plasticity in the regulatory function of AmrZ, we characterized the mode of regulation for this protein for swimming motility in P. stutzeri. As in P. syringae, AmrZ functions as a positive regulator of motility within P. stutzeri, which suggests that the functions of this protein with regards to swimming motility have switched at least twice across Pseudomonads. We further show that divergence between P. stutzeri and P. aeruginosa alleles of AmrZ does not explain shifts in regulatory mode. Further investigation into the mechanisms underlying shifts in regulatory function for AmrZ could provide unique insights into the evolution of bacterial regulatory proteins.

Author Comment

This is a preprint submission to PeerJ Preprints.